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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Genetic mapping and expression analysis of the murine DNA ligase I gene.

We mapped the murine DNA ligase I gene ( Lig1) in the mouse genome by using a mapping panel from an interspecific cross. Lig1 mapped to a centromeric part of chromosome 7, a region homologous to human chromosome 19q, where the human homologue LIG1 was localized. In addition, Lig1 expression was analyzed during the course of mouse liver-cell regeneration induced by partial hepatectomy, necrogenic doses of carbon tetrachloride, or the mitogen 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene. The results demonstrate that Lig1 is expressed in the liver during active cell proliferation.[1]

References

  1. Genetic mapping and expression analysis of the murine DNA ligase I gene. Gariboldi, M., Montecucco, A., Columbano, A., Ledda-Columbano, G.M., Savini, E., Manenti, G., Pierotti, M.A., Dragani, T.A. Mol. Carcinog. (1995) [Pubmed]
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