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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Heart fatty acid binding protein is a novel regulator of cardiac myocyte hypertrophy.

Heart fatty acid binding protein (H-FABP) is a 15kDa protein that mediates the passage of fatty acids from the plasma membrane to sites of lipid synthesis. We report here, for the first time, that H-FABP is a potent inducer of cardiac myocyte hypertrophy, stimulating an increase in cell surface area, protein synthesis and c-jun expression. A high affinity receptor for H-FABP has also been identified. Taken together, these data suggest that H-FABP may participate in the regulation of cardiac myocyte growth and differentiation.[1]

References

  1. Heart fatty acid binding protein is a novel regulator of cardiac myocyte hypertrophy. Burton, P.B., Hogben, C.E., Joannou, C.L., Clark, A.G., Hsuan, J.J., Totty, N.F., Sorensen, C., Evans, R.W., Tynan, M.J. Biochem. Biophys. Res. Commun. (1994) [Pubmed]
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