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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Localized scleroderma after exposure to organic solvents.

A 26-year-old female developed plaques characteristic of morphea on the volar surfaces of the forearms and on the dorsal surfaces on the ankles following an exposure to trichloroethylene, tetrachloroethylene and other solvents by inhalation. Exposure to chemicals has been known to be important as a provoking factor of systemic sclerosis. This patient shows that exposure to solvents could provoke localized scleroderma.[1]


  1. Localized scleroderma after exposure to organic solvents. Czirják, L., Pócs, E., Szegedi, G. Dermatology (Basel) (1994) [Pubmed]
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