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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Eosinophilic enterocolitis diagnosed by means of technetium-99m albumin scintigraphy and treated with budesonide ( CIR).

A patient with a 15 year history of diarrhoea of unknown origin is described. Scintigraphy with technetium-99m labelled albumin suggested albumin loss at the terminal ileum and caecum; subsequent colonoscopic biopsies of these macroscopically normal looking areas showed abundant infiltration with eosinophils. A diagnosis of eosinophilic enterocolitis was made. Treatment with prednisolone had good results, but had to be stopped because of severe side effects. Oral cromoglycate and mesalazine were not effective. Budesonide ( CIR), a new topically active corticosteroid with very little systemic effects, was at least as effective as prednisolone without producing side effects.[1]

References

  1. Eosinophilic enterocolitis diagnosed by means of technetium-99m albumin scintigraphy and treated with budesonide (CIR). Russel, M.G., Zeijen, R.N., Brummer, R.J., de Bruine, A.P., van Kroonenburgh, M.J., Stockbrügger, R.W. Gut (1994) [Pubmed]
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