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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Feeding and mating deterrency by sulfhydryl reagents in Triatoma infestans.

Topical application of different sulfhydryl (SH) reagents in acetone solution resulted in a deterrence of the feeding activity of Triatoma infestans nymph V. The ED50 for topical application of N-ethylmaleimide (NEM), the more active compound assayed, was 8.9 micrograms/insect. This effect showed a dose-dependent reversibility. We also observed feeding deterrency when a gauze cloth impregnated with NEM was located between the food source and the nymphs. After topical NEM treatment, mating deterrency was assessed by counting spermatophores dropped and eggs laid. When a population of adult insects, nymphal stages and eggs was reared in a cage containing filter papers treated with 0.4 mg/cm2 of NEM, a significant decrease of population density was seen after 200 days of exposure. Weekly replacement of filter papers impregnated with 0.13 mg/cm2 NEM for a period of one year enabled population control to be maintained. Antifeeding and antimating effects of NEM in Triatoma infestans and the resulting population control could be attributed to a chemoreceptor blockage produced by SH reagents.[1]

References

  1. Feeding and mating deterrency by sulfhydryl reagents in Triatoma infestans. Picollo, M.I., Seccacini, E., Vassena, C., Zerba, E. Acta Trop. (1993) [Pubmed]
 
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