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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Genetic analysis of the gene for porcine submaxillary gland mucin: physical assignment of the MUC and interferon gamma genes to chromosome 5.

Genetic variation at the porcine submaxillary gland mucin ( MUC) locus was revealed by RFLP analysis. A three-allele system was defined, and codominant inheritance was confirmed using a three-generation pedigree comprising 10 founder individuals, 26 F1 animals, and 200 F2 offspring. Linkage analysis was performed against a set of 56 genetic markers. The mucin locus was assigned to a previously reported linkage group comprising the markers interferon gamma ( IFNG), diacylglycerol kinase ( DAGK), and an anonymous microsatellite (S0092). Furthermore, the genes for mucin and interferon gamma were physically localized to porcine chromosome 5q2.3 and 5p1.2-q1.1 by fluorescence and radioactive in situ hybridization, respectively, thereby assigning four new markers to chromosome 5. This chromosome shares homologies with chromosome 5 in cattle and chromosome 12 in humans.[1]

References

  1. Genetic analysis of the gene for porcine submaxillary gland mucin: physical assignment of the MUC and interferon gamma genes to chromosome 5. Johansson, M., Chowdhary, B., Gu, F., Ellegren, H., Gustavsson, I., Andersson, L. J. Hered. (1993) [Pubmed]
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