- Clinical correlations of osteoarthritis associated with a single-base mutation (arginine519 to cysteine) in type II procollagen gene. A newly defined pathogenesis. Pun, Y.L., Moskowitz, R.W., Lie, S., Sundstrom, W.R., Block, S.R., McEwen, C., Williams, H.J., Bleasel, J.F., Holderbaum, D., Haqqi, T.M. Arthritis Rheum. (1994)