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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Ablation of luteal phase symptoms of Menière's disease with leuprolide.

Symptoms of Menière's disease in women may be exacerbated during the luteal phase of the menstrual cycle. This suggests a role for progesterone production and subsequent fluid redistribution as a predisposing factor for Menière's symptoms. We report the use of leuprolide acetate, a gonadotropin-releasing hormone agonist, in a woman with cyclic Menière's symptoms. This drug, which abolishes gonadotropin-dependent ovarian sex steroid production, alleviated the patient's symptoms during therapy. This observation offers further support to the hypothesis of sex hormone-related exacerbations of Menière's symptoms and provides a possible future treatment option for this debilitating disease.[1]

References

  1. Ablation of luteal phase symptoms of Menière's disease with leuprolide. Price, T.M., Allen, T.C., Bowyer, D.L., Watson, T.A. Arch. Otolaryngol. Head Neck Surg. (1994) [Pubmed]
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