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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Citrate anticoagulants for plateletpheresis.

In 112 plateletphereses done by the Haemonetics blood processor, the comparative effectiveness of ACD formula A, ACD formula B, and 2 per cent citrate in saline was evaluated. With respect to yields of platelets and white blood cells (e.g., lymphocytes), ACD-B was significantly better than the other two. Both ACD-B and 2 per cent citrate gave a much lower incidence of citrate reactions in the donors than were encountered with ACD-A.[1]


  1. Citrate anticoagulants for plateletpheresis. Huestis, D.W., Fletcher, J.L., White, R.F., Price, M.J. Transfusion (1977) [Pubmed]
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