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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Three cases of contact allergy after chemical burns from methylchloroisothiazolinone/methylisothiazolinone: one with concomitant allergy to methyldibromoglutaronitrile/phenoxyethanol.

BACKGROUND: Methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) is known to be a contact sensitizer. It is used extensively in cosmetic products in low concentrations. Occupational exposure usually occurs with concentrated solutions and results in a different reaction pattern. RESULTS: Three workers developed chemical burns and subsequent sensitization after exposure to concentrated solutions of MCI/MI. One patient was also occupationally sensitized to methyldibromoglutaronitrile/phenoxyethanol. CONCLUSION: Exposure to concentrated solutions of some allergens can be severely irritating in the occupational setting and can probably induce sensitization.[1]

References

  1. Three cases of contact allergy after chemical burns from methylchloroisothiazolinone/methylisothiazolinone: one with concomitant allergy to methyldibromoglutaronitrile/phenoxyethanol. Primka, E.J., Taylor, J.S. Am. J. Contact Dermatitis (1997) [Pubmed]
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