- How does cystitis affect a comparative risk profile of tiaprofenic acid with other non-steroidal antiinflammatory drugs? An international study based on spontaneous reports and drug usage data. ADR Signals Analysis Project (ASAP) Team. Lindquist, M., Pettersson, M., Edwards, I.R., Sanderson, J.H., Taylor, N.F., Fletcher, A.P., Schou, J.S., Savage, R. Pharmacol. Toxicol. (1997)