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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Partial purification of two lithocholic acid-binding proteins from rat liver 100 000g supernatants.

1. The partial purification of two lithocholic acid-binding proteins from liver 100 000g supernatants is described. 2. Gel-filtration, (NH4)2SO4 fractionation, Ca3(PO4)2 fractionation and ion-exchange chromatography were used. 3. Both proteins exhibited glutathione S-transferase activity; one may be the non-specific anion-binding protein ligandin. 4. Glutathione S-transferase activity of one of the binding proteins was inhibited by lithocholic acid.[1]

References

  1. Partial purification of two lithocholic acid-binding proteins from rat liver 100 000g supernatants. Strange, R.C., Cramb, R., Hayes, J.D., Percy-Robb, I.W. Biochem. J. (1977) [Pubmed]
 
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