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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

The effect of selenium on antioxidant system in erythrocytes and liver of the carp (Cyprinus carpio L.).

The effect of selenium-supplemented diet (sodium selenate and selenium yeast) on antioxidant in erythrocytes and liver of the carp (Cyprinus carpio L.) fingerlings was studied. With this goal, the activities of glutathione peroxidase (GSH-Px), catalase (CAT), superoxide dismutase (SOD), glutathione reductase ( GR) and glutathione-S-transferase (GST), as well as glutathione (GSH + GSSG) level, were determined. In the group supplemented with sodium selenate, no significant changes in the activity of the above enzymes were recorded in both the erythrocytes and in the liver, with the exception of GST activity that was significantly reduced in the plasma compared with the controls. Glutathione content was at the control level. In the group supplemented with selenium-yeast, the activities of GSH-Px, CAT, and SOD were significantly increased in erythrocytes, whereas GST activity and plasma content of GSH + GSSG were reduced compared with the controls. At the same time, the activities of hepatic SOD and GST were increased compared with the controls. These results demonstrate that organically bound selenium (selenium-yeast) acts more efficiently on antioxidant system of the carp fingerlings than inorganic selenium salts.[1]


  1. The effect of selenium on antioxidant system in erythrocytes and liver of the carp (Cyprinus carpio L.). Jovanovic, A., Grubor-Lajsic, G., Djukic, N., Gardinovacki, G., Matic, A., Spasic, M. Critical reviews in food science and nutrition. (1997) [Pubmed]
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