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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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'Sneeze syncope', basilar invagination and Arnold-Chiari type I malformation.

Syncope precipitated by sneezing in an adult male associated with an Arnold-Chiari type I malformation and basilar invagination presents a clinical problem in the differential diagnosis and pathological anatomy of Valsalva-related syncope. An abnormally acute clivoaxial angle, small foramen magnum, and type I Arnold-Chiari malformation appear to be a combination of features intolerant of Valsalva-induced changes in cerebral volume, brain-stem position, CSF fluid dynamics, or blood vessel relationships. Proposed mechanisms of pressure transmission to the area of intracranial pathology are discussed.[1]

References

  1. 'Sneeze syncope', basilar invagination and Arnold-Chiari type I malformation. Corbett, J.J., Butler, A.B., Kaufman, B. J. Neurol. Neurosurg. Psychiatr. (1976) [Pubmed]
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