Disease relevance of Arnold-Chiari Malformation

• We report a patient whose prolonged refractory headache was characterized by the clinical symptoms of occipital neuralgia, but was also associated with the radiographic appearance of an Arnold-Chiari malformation, type I and low CSF pressure [1].
• MR imaging also allowed characterization of a variety of abnormalities of the CNS (Arnold-Chiari malformation, Walker-Warburg syndrome, amniotic band syndrome) as well as of other structures (renal agenesis, multicystic dysplastic kidney, abdominal masses, severe limb-body wall defect, clubfoot with arthrogryposis, diaphragmatic hernia) [2].
• Congenital obstruction of A. co-existing with other CNS malformations, e.g. with spina bifida and the Arnold-Chiari malformation often associated with hydrocephalus, or with hydranencephaly where A. stenosis is primary or secondary in origin [3].
• Use of caffeine in the treatment of apnea associated with the Arnold-Chiari malformation [4].
• Among the findings associated with the human Retinoic Acid Embryopathy are hindbrain defects including the Arnold-Chiari malformation [5].

High impact information on Arnold-Chiari Malformation

• An abnormally acute clivoaxial angle, small foramen magnum, and type I Arnold-Chiari malformation appear to be a combination of features intolerant of Valsalva-induced changes in cerebral volume, brain-stem position, CSF fluid dynamics, or blood vessel relationships [6].
• Arnold-Chiari malformation with syrinx presenting as carpal tunnel syndrome: a case report [7].
• Lithium-induced downbeat nystagmus in a patient with Arnold-Chiari malformation [8].
• Dose-response relationships of retinol in production of the Arnold-Chiari malformation [9].
• Anesthetic management of a child with Arnold-Chiari malformation and Klippel-Feil syndrome [10].

Chemical compound and disease context of Arnold-Chiari Malformation

• In addition, the value of metrizamide cisternography in diagnosing the Arnold-Chiari malformation is illustrated [11].

Gene context of Arnold-Chiari Malformation

• Two hydrocephalic Hy 3 mice and an infant with hydrocephalus and the Arnold-Chiari malformation were examined with the scanning electron microscope [12].
• Of those with glial tissue, the eight without Arnold-Chiari malformation were myelocystocele associated with cloacal exstrophy (six), caudal regression syndrome (one), and microcephaly (one) [13].
• Patients with cerebellar lesions due to the Arnold-Chiari malformation showed behavior that was intermediate between that of normal subjects and the patients with midline lesions [14].
• A case of syringomyelia with type I Arnold-Chiari malformation (ACM): growth hormone (GH) therapy and the size of syrinx on serial MR images [15].
• Hydroephalus of childhood may be associated with intracranial haemorrhage, infection, aqueductal stenosis, Arnold-Chiari malformation (spina bifida), tumours or more uncommonly with the Dandy-Walker syndrome (DWS) [16].

Analytical, diagnostic and therapeutic context of Arnold-Chiari Malformation

• Adult Arnold-Chiari malformation type I demonstrated by CT metrizamide myelography [17].
• Multiple imaging techniques. CSF shunted Arnold Chiari malformation with false-negative brain death radionuclide angiograms [18].

References