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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

COI1: an Arabidopsis gene required for jasmonate-regulated defense and fertility.

The coi1 mutation defines an Arabidopsis gene required for response to jasmonates, which regulate defense against insects and pathogens, wound healing, and pollen fertility. The wild-type allele, COI1, was mapped to a 90-kilobase genomic fragment and located by complementation of coi1-1 mutants. The predicted amino acid sequence of the COI1 protein contains 16 leucine-rich repeats and an F-box motif. It has similarity to the F-box proteins Arabidopsis TIR1, human Skp2, and yeast Grr1, which appear to function by targeting repressor proteins for removal by ubiquitination.[1]


  1. COI1: an Arabidopsis gene required for jasmonate-regulated defense and fertility. Xie, D.X., Feys, B.F., James, S., Nieto-Rostro, M., Turner, J.G. Science (1998) [Pubmed]
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