Gene Review:
SKP2 - putative SCF ubiquitin ligase complex...
Saccharomyces cerevisiae S288c
Synonyms:
F-box protein SKP2, N0376, YNL311C
- The F box protein Dsg1/Mdm30 is a transcriptional coactivator that stimulates Gal4 turnover and cotranscriptional mRNA processing. Muratani, M., Kung, C., Shokat, K.M., Tansey, W.P. Cell (2005)
- SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box. Bai, C., Sen, P., Hofmann, K., Ma, L., Goebl, M., Harper, J.W., Elledge, S.J. Cell (1996)
- Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Schulman, B.A., Carrano, A.C., Jeffrey, P.D., Bowen, Z., Kinnucan, E.R., Finnin, M.S., Elledge, S.J., Harper, J.W., Pagano, M., Pavletich, N.P. Nature (2000)
- Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle. Freed, E., Lacey, K.R., Huie, P., Lyapina, S.A., Deshaies, R.J., Stearns, T., Jackson, P.K. Genes Dev. (1999)
- Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast. Patton, E.E., Willems, A.R., Sa, D., Kuras, L., Thomas, D., Craig, K.L., Tyers, M. Genes Dev. (1998)
- Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis. Patton, E.E., Willems, A.R., Tyers, M. Trends Genet. (1998)
- SCF ubiquitin protein ligases and phosphorylation-dependent proteolysis. Willems, A.R., Goh, T., Taylor, L., Chernushevich, I., Shevchenko, A., Tyers, M. Philos. Trans. R. Soc. Lond., B, Biol. Sci. (1999)
- Cdc34 and the F-box protein Met30 are required for degradation of the Cdk-inhibitory kinase Swe1. Kaiser, P., Sia, R.A., Bardes, E.G., Lew, D.J., Reed, S.I. Genes Dev. (1998)
- The unstable F-box protein p58-Ctf13 forms the structural core of the CBF3 kinetochore complex. Russell, I.D., Grancell, A.S., Sorger, P.K. J. Cell Biol. (1999)
- The F-box protein Rcy1p is involved in endocytic membrane traffic and recycling out of an early endosome in Saccharomyces cerevisiae. Wiederkehr, A., Avaro, S., Prescianotto-Baschong, C., Haguenauer-Tsapis, R., Riezman, H. J. Cell Biol. (2000)
- Mdm30 is an F-box protein required for maintenance of fusion-competent mitochondria in yeast. Fritz, S., Weinbach, N., Westermann, B. Mol. Biol. Cell (2003)
- Ypt31/32 GTPases and their novel F-box effector protein Rcy1 regulate protein recycling. Chen, S.H., Chen, S., Tokarev, A.A., Liu, F., Jedd, G., Segev, N. Mol. Biol. Cell (2005)
- F-box protein Grr1 interacts with phosphorylated targets via the cationic surface of its leucine-rich repeat. Hsiung, Y.G., Chang, H.C., Pellequer, J.L., La Valle, R., Lanker, S., Wittenberg, C. Mol. Cell. Biol. (2001)
- Grr1-dependent inactivation of Mth1 mediates glucose-induced dissociation of Rgt1 from HXT gene promoters. Flick, K.M., Spielewoy, N., Kalashnikova, T.I., Guaderrama, M., Zhu, Q., Chang, H.C., Wittenberg, C. Mol. Biol. Cell (2003)
- Null mutation of AtCUL1 causes arrest in early embryogenesis in Arabidopsis. Shen, W.H., Parmentier, Y., Hellmann, H., Lechner, E., Dong, A., Masson, J., Granier, F., Lepiniec, L., Estelle, M., Genschik, P. Mol. Biol. Cell (2002)
- Proteasome- and SCF-dependent degradation of yeast adenine deaminase upon transition from proliferation to quiescence requires a new F-box protein named Saf1p. Escusa, S., Camblong, J., Galan, J.M., Pinson, B., Daignan-Fornier, B. Mol. Microbiol. (2006)
- Identification of F-box proteins that are involved in resistance to methylmercury in Saccharomyces cerevisiae. Hwang, G.W., Ishida, Y., Naganuma, A. FEBS Lett. (2006)
- Functions of the DNA damage response pathway target Ho endonuclease of yeast for degradation via the ubiquitin-26S proteasome system. Kaplun, L., Ivantsiv, Y., Kornitzer, D., Raveh, D. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Skp1p regulates soi3p/rav1p association with endosomal membranes but is not required for vacuolar ATPase assembly. Brace, E.J., Parkinson, L.P., Fuller, R.S. Eukaryotic Cell (2006)
- Skp1p and the F-box protein Rcy1p form a non-SCF complex involved in recycling of the SNARE Snc1p in yeast. Galan, J.M., Wiederkehr, A., Seol, J.H., Haguenauer-Tsapis, R., Deshaies, R.J., Riezman, H., Peter, M. Mol. Cell. Biol. (2001)
- Overexpression of Arabidopsis thaliana SKP1 homologues in yeast inactivates the Mig1 repressor by destabilising the F-box protein Grr1. Schouten, J., de Kam, R.J., Fetter, K., Hoge, J.H. Mol. Gen. Genet. (2000)
- Functional interaction of 13 yeast SCF complexes with a set of yeast E2 enzymes in vitro. Kus, B.M., Caldon, C.E., Andorn-Broza, R., Edwards, A.M. Proteins (2004)
- Instability of the mitofusin Fzo1 regulates mitochondrial morphology during the mating response of the yeast Saccharomyces cerevisiae. Neutzner, A., Youle, R.J. J. Biol. Chem. (2005)
- The novel F-box protein Mfb1p regulates mitochondrial connectivity and exhibits asymmetric localization in yeast. Kondo-Okamoto, N., Ohkuni, K., Kitagawa, K., McCaffery, J.M., Shaw, J.M., Okamoto, K. Mol. Biol. Cell (2006)
- Amino acid signaling in Saccharomyces cerevisiae: a permease-like sensor of external amino acids and F-Box protein Grr1p are required for transcriptional induction of the AGP1 gene, which encodes a broad-specificity amino acid permease. Iraqui, I., Vissers, S., Bernard, F., de Craene, J.O., Boles, E., Urrestarazu, A., André, B. Mol. Cell. Biol. (1999)
- An additional role for the F-box motif: gene regulation within the Neurospora crassa sulfur control network. Kumar, A., Paietta, J.V. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Skp1 and the F-box protein Pof6 are essential for cell separation in fission yeast. Hermand, D., Bamps, S., Tafforeau, L., Vandenhaute, J., Mäkelä, T.P. J. Biol. Chem. (2003)