- Herpes simplex virus glycoprotein D can bind to poliovirus receptor-related protein 1 or herpesvirus entry mediator, two structurally unrelated mediators of virus entry. Krummenacher, C., Nicola, A.V., Whitbeck, J.C., Lou, H., Hou, W., Lambris, J.D., Geraghty, R.J., Spear, P.G., Cohen, G.H., Eisenberg, R.J. J. Virol. (1998)