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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Novel defensin subfamily from spinach (Spinacia oleracea).

Antimicrobial peptides (So-D1-7) were isolated from a crude cell wall preparation from spinach leaves (Spinacia oleracea cv. Matador) and, judged from their amino acid sequences, six of them (So-D2-7) represented a novel structural subfamily of plant defensins (group IV). Group-IV defensins were also functionally distinct from those of groups I-III. They were active at concentrations < 20 microM against Gram-positive (Clavibacter michiganensis) and Gram-negative (Ralstonia solanacearum) bacterial pathogens, as well as against fungi, such as Fusarium culmorum, F. solani, Bipolaris maydis, and Colletotrichum lagenarium. Fungal inhibition occurred without hyphal branching. Group-IV defensins were preferentially distributed in the epidermal cell layer of leaves and in the subepidermal region of stems.[1]


  1. Novel defensin subfamily from spinach (Spinacia oleracea). Segura, A., Moreno, M., Molina, A., García-Olmedo, F. FEBS Lett. (1998) [Pubmed]
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