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Chemical Compound Review

Scimitar     [cyano-(3- phenoxyphenyl)methyl] (1S,3S)-3...

Synonyms: Grenade, Matador, CYHALOTHRIN, Saber, Cyhalothrine, ...
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Disease relevance of Grenade


High impact information on Grenade

  • The clinical, catheterization and imaging data of 13 consecutive infants with scimitar syndrome who underwent cardiac catheterization in the 1st 6 months of life were reviewed, with emphasis on the pulmonary artery pressure, pulmonary and cardiovascular anatomy, therapeutic interventions and outcome [1].
  • In a patient with the scimitar syndrome duplex Doppler sonography was used to show the point of entry of the abnormal pulmonary vein into the inferior vena cava to determine blood flow [6].
  • Scimitar-horned oryx spermatozoa appear relatively tolerant of varied cryopreservation methods, and preserved samples exhibit adequate post-thaw function to warrant use for assisted reproduction [7].
  • Antimicrobial peptides (So-D1-7) were isolated from a crude cell wall preparation from spinach leaves (Spinacia oleracea cv. Matador) and, judged from their amino acid sequences, six of them (So-D2-7) represented a novel structural subfamily of plant defensins (group IV) [8].
  • Heterologous in vitro fertilization and sperm capacitation in an endangered African antelope, the scimitar-horned oryx (Oryx dammah) [9].

Chemical compound and disease context of Grenade


Biological context of Grenade


Anatomical context of Grenade


Associations of Grenade with other chemical compounds


Gene context of Grenade

  • Scimitar sign with normal pulmonary venous drainage and anomalous inferior vena cava [21].
  • The classic definition of the scimitar syndrome is a triad of hypoplasia of the right lung with anomalous venous drainage and a systemic arterial supply of a variable degree [4].
  • During repair, creation of an atrial septal defect in the distorted septal-left atrial junction of scimitar syndrome is facilitated by first incising the anteromedial aspect of the fossa ovalis to better delineate the optimal posterolateral margin [22].
  • Pediatric case of the day. Hypogenetic lung syndrome (scimitar syndrome) with right-sided congenital diaphragmatic hernia [23].
  • Significantly higher perinatal mortality was found in species which breed throughout the year (notably axis deer and sitatunga) than in seasonal breeders, and differences associated with system of management were apparent in some species (eg, mouflon and scimitar-horned oryx) kept at Regent's Park and Whipsnade [24].

Analytical, diagnostic and therapeutic context of Grenade


  1. Scimitar syndrome in infancy. Gao, Y.A., Burrows, P.E., Benson, L.N., Rabinovitch, M., Freedom, R.M. J. Am. Coll. Cardiol. (1993) [Pubmed]
  2. The crossover lung segment: congenital malformation associated with a variant of scimitar syndrome. Clements, B.S., Warner, J.O. Thorax (1987) [Pubmed]
  3. Scimitar syndrome with peripheral left pulmonary artery branch stenoses. Platia, E.V., Brinker, J.A. Am. Heart J. (1984) [Pubmed]
  4. Scimitar sign with normal pulmonary venous drainage and systemic arterial supply. Scimitar syndrome or bronchopulmonary sequestration? Cukier, A., Kavakama, J., Teixeira, L.R., Terra-Filho, M., Vargas, F.S. Chest (1994) [Pubmed]
  5. Anterior sacral meningocele and the scimitar sign. Report of a case. Kovalcik, P.J., Burke, J.B. Dis. Colon Rectum (1988) [Pubmed]
  6. Anomalous pulmonary venous drainage shown by duplex sonography, computed tomography, and plain radiography. Huebsch, P., Neuhold, A., Mayr, H., Glogar, D. Thorax (1989) [Pubmed]
  7. Scimitar-horned oryx (Oryx dammah) spermatozoa are functionally competent in a heterologous bovine in vitro fertilization system after cryopreservation on dry ice, in a dry shipper, or over liquid nitrogen vapor. Roth, T.L., Bush, L.M., Wildt, D.E., Weiss, R.B. Biol. Reprod. (1999) [Pubmed]
  8. Novel defensin subfamily from spinach (Spinacia oleracea). Segura, A., Moreno, M., Molina, A., García-Olmedo, F. FEBS Lett. (1998) [Pubmed]
  9. Heterologous in vitro fertilization and sperm capacitation in an endangered African antelope, the scimitar-horned oryx (Oryx dammah). Roth, T.L., Weiss, R.B., Buff, J.L., Bush, L.M., Wildt, D.E., Bush, M. Biol. Reprod. (1998) [Pubmed]
  10. Electrophysiologic mechanisms and electrocardiographic findings in atrioventricular-nodal reentrant tachycardia in a patient with the scimitar syndrome. Bakker, R., de Weerd, G. Heart & lung : the journal of critical care. (1997) [Pubmed]
  11. False pulmonary artery catheter measurements due to the scimitar (hypogenetic lung) syndrome. Potential for iatrogenic pulmonary edema. Pomerantz, S.M., Mirvis, S.E., Siegel, E.L., Belzberg, H. Chest (1993) [Pubmed]
  12. Scimitar syndrome presenting in infancy. Huddleston, C.B., Exil, V., Canter, C.E., Mendeloff, E.N. Ann. Thorac. Surg. (1999) [Pubmed]
  13. Intraocular pressure and tear production in five herbivorous wildlife species. Ofri, R., Horowitz, I.H., Raz, D., Shvartsman, E., Kass, P.H. Vet. Rec. (2002) [Pubmed]
  14. Comparing ovulation synchronization protocols for artificial insemination in the scimitar-horned oryx (Oryx dammah). Morrow, C.J., Wolfe, B.A., Roth, T.L., Wildt, D.E., Bush, M., Blumer, E.S., Atkinson, M.W., Monfort, S.L. Anim. Reprod. Sci. (2000) [Pubmed]
  15. Two cases of scimitar variant. Takeda, S., Imachi, T., Arimitsu, K., Minami, M., Hayakawa, M. Chest (1994) [Pubmed]
  16. Anterior sacral meningocele: two case reports and discussion of surgical approach. Smith, H.P., Davis, C.H. Neurosurgery (1980) [Pubmed]
  17. Combined correction of an adult scimitar syndrome and coronary artery bypass grafting. Walles, T., Lichtenberg, A., Shiraga, K., Klima, U. Ann. Thorac. Surg. (2002) [Pubmed]
  18. Effectiveness of botulinum toxin type A against painful limb myoclonus of spinal cord origin. Polo, K.B., Jabbari, B. Mov. Disord. (1994) [Pubmed]
  19. Gadolinium-enhanced magnetic resonance angiography in scimitar syndrome: diagnosis and postoperative evaluation. Gilkeson, R.C., Lee, J.H., Sachs, P.B., Clampitt, M. Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital. (2000) [Pubmed]
  20. Pharmacokinetics of a single intravenous enrofloxacin dose in scimitar-horned oryx (Oryx dammah). Gamble, K.C., Boothe, D.M., Jensen, J.M., Heatley, J.J., Helmick, K.E. J. Zoo Wildl. Med. (1997) [Pubmed]
  21. Scimitar sign with normal pulmonary venous drainage and anomalous inferior vena cava. Herer, B., Jaubert, F., Delaisements, C., Huchon, G., Chretien, J. Thorax (1988) [Pubmed]
  22. Correction of anomalous subdiaphragmatic inferior vena caval drainage of the right pulmonary veins (scimitar syndrome). Tobin, G.R., Anderson, R.M., Arem, A.J. Ann. Thorac. Surg. (1977) [Pubmed]
  23. Pediatric case of the day. Hypogenetic lung syndrome (scimitar syndrome) with right-sided congenital diaphragmatic hernia. Cairns, R.A., Culham, J.A., Stringer, D.A., Murphy, J.J. Radiographics : a review publication of the Radiological Society of North America, Inc. (1995) [Pubmed]
  24. Perinatal mortality and season of birth in captive wild ungulates. Kirkwood, J.K., Gaskin, C.D., Markham, J. Vet. Rec. (1987) [Pubmed]
  25. The Scimitar syndrome: CT findings in partial anomalous pulmonary venous return. Olson, M.A., Becker, G.J. Radiology. (1986) [Pubmed]
  26. The scimitar syndrome: clinical spectrum and surgical treatment. Schramel, F.M., Westermann, C.J., Knaepen, P.J., van den Bosch, J.M. Eur. Respir. J. (1995) [Pubmed]
  27. Scimitar syndrome: cine magnetic resonance imaging demonstration of anomalous pulmonary venous drainage. Baxter, R., McFadden, P.M., Gradman, M., Wright, A. Ann. Thorac. Surg. (1990) [Pubmed]
  28. Surgical management of scimitar syndrome: an alternative approach. Brown, J.W., Ruzmetov, M., Minnich, D.J., Vijay, P., Edwards, C.A., Uhlig, P.N., Fiore, A.C., Turrentine, M.W. J. Thorac. Cardiovasc. Surg. (2003) [Pubmed]
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