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Chemical Compound Review

Metafolin     (2S)-2-[[4-[[(6S)-2-amino-5- methyl-4-oxo-1...

Synonyms: LEVOMEFOLATE, LMSR, Metafolin (TN), SureCN79586, CHEMBL1231574, ...
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Disease relevance of 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID


Psychiatry related information on 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID


High impact information on 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID


Chemical compound and disease context of 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID


Biological context of 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID


Anatomical context of 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID


Associations of 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID with other chemical compounds


Gene context of 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID

  • This trap results from the fact that 5MTHF can neither be metabolised via the methionine synthase pathway, nor can it be reconverted to its precursor, methylenetetrahydrofolate [11].
  • In the copper-induced LDL oxidation system, vitamin B-12 and 5-methyltetrahydrofolic acid increased the lag time of conjugated diene production by 25 and 47%, respectively, suggesting that both vitamins in this system had antioxidant properties [19].
  • The selective MS detection and identification of endogenous 5-methyltetrahydrofolic acid in human plasma was accomplished through the development of a straightforward C18-based solid-phase extraction procedure [23].


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  19. Effect of homocysteine, folates, and cobalamin on endothelial cell- and copper-induced LDL oxidation. Ronco, A.M., Garrido, A., Llanos, M.N., Guerrero-Bosagna, C., Tamayo, D., Hirsch, S. Lipids (2005) [Pubmed]
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