Gene Review:
Tnfsf12 - tumor necrosis factor (ligand) superfamily...
Mus musculus
Synonyms:
APO3L, Apo3l, DR3L, Dr3l, Dr3lg, ...
- Proinflammatory effects of TWEAK/Fn14 interactions in glomerular mesangial cells. Campbell, S., Burkly, L.C., Gao, H.X., Berman, J.W., Su, L., Browning, B., Zheng, T., Schiffer, L., Michaelson, J.S., Putterman, C. J. Immunol. (2006)
- TWEAK attenuates the transition from innate to adaptive immunity. Maecker, H., Varfolomeev, E., Kischkel, F., Lawrence, D., LeBlanc, H., Lee, W., Hurst, S., Danilenko, D., Li, J., Filvaroff, E., Yang, B., Daniel, D., Ashkenazi, A. Cell (2005)
- TWEAK induces liver progenitor cell proliferation. Jakubowski, A., Ambrose, C., Parr, M., Lincecum, J.M., Wang, M.Z., Zheng, T.S., Browning, B., Michaelson, J.S., Baetscher, M., Baestcher, M., Wang, B., Bissell, D.M., Burkly, L.C. J. Clin. Invest. (2005)
- TWEAK/Fn14 interactions are instrumental in the pathogenesis of nephritis in the chronic graft-versus-host model of systemic lupus erythematosus. Zhao, Z., Burkly, L.C., Campbell, S., Schwartz, N., Molano, A., Choudhury, A., Eisenberg, R.A., Michaelson, J.S., Putterman, C. J. Immunol. (2007)
- TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration. Girgenrath, M., Weng, S., Kostek, C.A., Browning, B., Wang, M., Brown, S.A., Winkles, J.A., Michaelson, J.S., Allaire, N., Schneider, P., Scott, M.L., Hsu, Y.M., Yagita, H., Flavell, R.A., Miller, J.B., Burkly, L.C., Zheng, T.S. EMBO J. (2006)
- Tumor necrosis factor-like weak inducer of apoptosis-induced neurodegeneration. Potrovita, I., Zhang, W., Burkly, L., Hahm, K., Lincecum, J., Wang, M.Z., Maurer, M.H., Rossner, M., Schneider, A., Schwaninger, M. J. Neurosci. (2004)
- Down-regulated expression of TWEAK mRNA in acute and chronic inflammatory pathologies. Chicheportiche, Y., Fossati-Jimack, L., Moll, S., Ibnou-Zekri, N., Izui, S. Biochem. Biophys. Res. Commun. (2000)
- A soluble Fn14-Fc decoy receptor reduces infarct volume in a murine model of cerebral ischemia. Yepes, M., Brown, S.A., Moore, E.G., Smith, E.P., Lawrence, D.A., Winkles, J.A. Am. J. Pathol. (2005)
- TWEAK is a novel arthritogenic mediator. Perper, S.J., Browning, B., Burkly, L.C., Weng, S., Gao, C., Giza, K., Su, L., Tarilonte, L., Crowell, T., Rajman, L., Runkel, L., Scott, M., Atkins, G.J., Findlay, D.M., Zheng, T.S., Hess, H. J. Immunol. (2006)
- The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation. Brown, S.A., Richards, C.M., Hanscom, H.N., Feng, S.L., Winkles, J.A. Biochem. J. (2003)
- TWEAK mediates signal transduction and differentiation of RAW264.7 cells in the absence of Fn14/TweakR. Evidence for a second TWEAK receptor. Polek, T.C., Talpaz, M., Darnay, B.G., Spivak-Kroizman, T. J. Biol. Chem. (2003)
- TWEAK mediates anti-tumor effect of tumor-infiltrating macrophage. Kaduka, Y., Takeda, K., Nakayama, M., Kinoshita, K., Yagita, H., Okumura, K. Biochem. Biophys. Res. Commun. (2005)
- Intraovarian tumor necrosis factor-related weak inducer of apoptosis/fibroblast growth factor-inducible-14 ligand-receptor system limits ovarian preovulatory follicles from excessive luteinization. De, A., Park, J.I., Kawamura, K., Chen, R., Klein, C., Rauch, R., Mulders, S.M., Sollewijn Gelpke, M.D., Hsueh, A.J. Mol. Endocrinol. (2006)
- Characterization of murine TWEAK and its receptor (Fn14) by monoclonal antibodies. Nakayama, M., Harada, N., Okumura, K., Yagita, H. Biochem. Biophys. Res. Commun. (2003)
- Tumor necrosis factor-like weak inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor-kappaB and degradation of MyoD protein. Dogra, C., Changotra, H., Mohan, S., Kumar, A. J. Biol. Chem. (2006)
- Tumor necrosis factor-like weak inducer of apoptosis increases the permeability of the neurovascular unit through nuclear factor-kappa B pathway activation. Polavarapu, R., Gongora, M.C., Winkles, J.A., Yepes, M. J. Neurosci. (2005)
- TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation. Saitoh, T., Nakayama, M., Nakano, H., Yagita, H., Yamamoto, N., Yamaoka, S. J. Biol. Chem. (2003)
- NF-kappaB signalling in cerebral ischaemia. Schwaninger, M., Inta, I., Herrmann, O. Biochem. Soc. Trans. (2006)
- Targeting fibroblast growth factor-inducible-14 signaling protects from chronic relapsing experimental autoimmune encephalomyelitis. Mueller, A.M., Pedré, X., Kleiter, I., Hornberg, M., Steinbrecher, A., Giegerich, G. J. Neuroimmunol. (2005)