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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 55 documents. Results 1 - 10.

Mus musculus
Gene: ... Disease relevance of Gbx2 The cDNA sequence of Stra7, a retinoic acid( RA )- inducible gene in P19 embryonal carcinoma( EC) cells, was determined. High impact information on Gbx2 In mice, Otx2 is expressed in the forebrain and midbrain and Gbx2 is expressed in the anterior hindbrain, with a shared border at the level... / Synonyms: Gbx-2; Homeobox protein GBX-2
Xenopus laevis
Gene: ... High impact information on Gbx2b The border between the transcription domains of Otx2 and Gbx2.... Gbx2 homeobox genes are important for formation and function of the midbrain/ hindbrain boundary, namely the isthmic organizer. Associations of Gbx2b with chemical compounds We demonstrate that protein... / Synonyms: Gbx2; gbx2b
Danio rerio
Gene: ... High impact information on gbx2 In zebrafish, sequential expression of gbx1 and gbx2 in the anterior hindbrain contributes to this process, whereas in mouse embryos, a single Gbx gene( Gbx2..., as well as gbx2 expression in r1, was missing in no isthmus mutant embryos that lacked functional pax2a... / Synonyms: gbx-2
Homo sapiens
Gene: ... Disease relevance of GBX2 When implanted s. c. into nude mice, the tumorigenicity of the antisense GBX2 transfectants from both human prostatic cancer cell lines was inhibited by more than 70% compared to the parental cells. High impact information on GBX2 Otx2 and Gbx2 can repress the expression of each other... / Synonyms: Homeobox protein GBX-2
Rattus norvegicus
Gene: ... High impact information on Gbx2 Mid/ hindbrain organizer gene expression, however, continues to be dependent on Gbx2. Moreover, we also show that FGF8 protein is sufficient to induce an ectopic isthmic organiser( Fgf- 8 +, Gbx2 +) in anterior midbrain....
Gallus gallus
Gene: ... High impact information on GBX2 Ectopic expression of GBX2 in growth factor- dependent myeloblasts...- transformed cells. The homeobox gene GBX2, a target of the myb oncogene, mediates autocrine growth and monocyte differentiation. GBX2 activation by c- Myb requires signal transduction emanating from the cell...
MeSH term: ... in the forebrain and midbrain and Gbx2 is expressed in the anterior hindbrain, with a shared border at the level...
MeSH term: ... / hindbrain organizer gene expression, however, continues to be dependent on Gbx2. Anatomical context... for Gbx2 in repression of Otx2 and positioning the mid/ hindbrain organizer. On the basis...
MeSH term: ... thalamus for the Gbx- 2 and Wnt- 3 genes. Consequently, development of the dorsal and ventral thalamus... in regulation of appetite and resting energy expenditure, is identical. After birth, all mutant mice develop...
MeSH term: ... the leukemogenic potential of PML- RARalpha. Ectopic expression of GBX2 in growth factor- dependent myeloblasts... and promyelocytes, and expansion of myeloid progenitor populations -- all characteristics of AML. To tackle... with interleukin 5, essentially all nonadherent cells in both bone marrow and cord blood cell cultures became...

 

 
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