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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 112 documents. Results 1 - 10.

Homo sapiens
Gene: ... Disease relevance of MCL1 They further show that MCL1 has sequence similarity to BCL2, a gene.... This report describes a gene, MCL1, that we isolated from the ML- 1 human myeloid leukemia cell line during... of human chromosome 1, where MCL1 is located, is duplicated and/ or rearranged in a variety... / Synonyms: Bcl-2-related protein EAT/mcl1; Induced myeloid leukemia cell differentiation protein Mcl-1; MCL1-ES
Mus musculus
Gene: ... Disease relevance of Mcl1 Up- regulated expression of murine Mcl1/ EAT, a bcl- 2 related gene..., enforced Mcl- 1 expression in a mouse lymphoma model conferred resistance. Mcl- 1 promoter activity... CAR effect on Mcl- 1 transcription. Increased expression of Mcl- 1 is required for protection against... / Synonyms: Bcl-2-related protein EAT/mcl1; Induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Mcl-1
Rattus norvegicus
Gene: ... High impact information on Mcl1 These results suggested that removal of N- terminal domains of Bid by caspase- 8 and Mcl- 1 by caspase- 3 enabled the maximal mitochondrial perturbation that potentiated TRAIL- induced apoptosis. We further established for the first time that the C- terminal domain of Mcl- 1 became... / Synonyms: Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
Danio rerio
Gene: ... Disease relevance of mcl1a Imbalance in liver homeostasis leading to hyperplasia by overexpressing either one of the Bcl- 2- related genes, zfBLP1 and zfMcl- 1a. High impact information on mcl1a Increased... zfBLP1 or zfMcl- 1a.( This finding may have been due to liver abnormalities that led to failure... / Synonyms: zfMcl-1a
Ovis aries
Gene: ... High impact information on MCL1 Intron polymorphisms were used for linkage mapping of BAX and MCL1, which were mapped on OAR14 and OAR1 respectively....
Xenopus (Silurana) tropicalis
Gene: Synonyms: mcl-1; mcl1l; mcl1s
Chemical compound: ... Mcl- 1 in both cell lines and primary lymphocytes via inhibitory phosphorylation of glycogen synthase kinase 3alpha and 3beta( GSK- 3alpha/ beta ), which otherwise promoted Mcl- 1 degradation. Each pathway...
Chemical compound: ... and patients with RA. While TNFalpha had no effect on MCL- 1 transcription, it induced expression of another... of septic shock remains imperative as all investigational therapies, including anti- tumor necrosis factor...
Schizosaccharomyces pombe 972h-
Gene
MeSH term: ... Myeloid Cell Leukemia 1( MCL- 1). Taken together, these data suggest that neurofibromin is required...). It is well known that all- trans- retinoic acid( ATRA) can induce myeloid cell differentiation in acute... progenitor kinase ), which is expressed in all stages of the B lineage and in myeloid cells. P- selectin...

 

 
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