Your search matched a total of 110 documents. Results 1 - 10.
Mus musculus
Gene: ... Disease relevance of Nkx2- 5 To define these pathways, we generated mice with a ventricular- restricted knockout of Nkx2- 5, which display no structural defects but have progressive complete heart block, and massive trabecular muscle overgrowth found in some patients with Nkx2- 5 mutations. In order to establish... / Synonyms: Homeobox protein Nkx-2.5; Nkx-2.5; Nkx2.5
Gallus gallus
Gene: ... High impact information on NKX2- 5 By contrast, overexpression of a human NKX2- 5 mutant did.... Differentiation of cardiac Purkinje fibers requires precise spatiotemporal regulation of Nkx2- 5 expression. Overexpression of Nkx2- 5 caused inhibition of slow tonic myosin heavy chain protein( sMHC ), a late Purkinje... / Synonyms: NKX-2.5
Rattus norvegicus
Gene: ... Disease relevance of Nkx2- 5 Interestingly, coincident with NIS expression, Nkx- 2. 5 m... that activation of GATA- 4, in cooperation with a factor binding on Nkx- 2. 5 binding element, is essential for mechanical stretch- induced cardiomyocyte hypertrophy. Functional analyses of three Csx/ Nkx- 2. 5 mutations... / Synonyms: Homeobox protein Nkx-2.5; Nkx-2.5; Nkx2.5
Homo sapiens
Gene: ... in pediatric T- ALL cell lines via a novel t( 5; 14 )( q35. 1; q32. 2). BACKGROUND: Mutations in NKX2- 5 have...- time quantitative PCR in the T- ALL case with the NKX2- 5- TRD rearrangement, 18 other cases of T- ALL...Disease relevance of NKX2- 5 Congenital heart disease caused by mutations in the transcription... / Synonyms: Homeobox protein Nkx-2.5; NKX2.5
Danio rerio
Gene: ... High impact information on nkx2. 5 Together, these results implicate zebrafish Gata5 in controlling... the expression of the early myocardial gene nkx2. 5. Forced expression of gata5 in swr/ bmp2b and Zoep mutants restores robust nkx2. 5 expression. Embryos lacking zygotic oep( Zoep mutants) display cardia bifida and... / Synonyms: nkx2-5
MeSH term: ... - mediated cytotoxicity in parallel. Postnatal conduction defects in Nkx2- 5 mutation may result at least...
MeSH term: ... cardiac hypertrophy and heart failure that mimic human heart disease. Nkx2- 5 pathways and congenital... examined biochemical interactions of mutant Eya4 peptides. The cardiac homeobox protein Nkx2- 5 is essential in cardiac development, and mutations in Csx( which encodes Nkx2- 5) cause various congenital...
MeSH term: ... and activates the ANF gene, at least in part, by associating with the cardiac homeodomain protein Nkx2- 5. Here...
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Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
