Gene Review:
Nkx2-5 - NK2 homeobox 5
Rattus norvegicus
Synonyms:
Csx, Homeobox protein NK-2 homolog E, Homeobox protein Nkx-2.5, Nkx-2.5, Nkx2.5, ...
- Transcription factor Nkx-2.5 induces sodium/iodide symporter gene expression and participates in retinoic acid- and lactation-induced transcription in mammary cells. Dentice, M., Luongo, C., Elefante, A., Romino, R., Ambrosio, R., Vitale, M., Rossi, G., Fenzi, G., Salvatore, D. Mol. Cell. Biol. (2004)
- GATA-4 is a nuclear mediator of mechanical stretch-activated hypertrophic program. Pikkarainen, S., Tokola, H., Majalahti-Palviainen, T., Kerkela, R., Hautala, N., Bhalla, S.S., Charron, F., Nemer, M., Vuolteenaho, O., Ruskoaho, H. J. Biol. Chem. (2003)
- Functional analyses of three Csx/Nkx-2.5 mutations that cause human congenital heart disease. Zhu, W., Shiojima, I., Hiroi, Y., Zou, Y., Akazawa, H., Mizukami, M., Toko, H., Yazaki, Y., Nagai, R., Komuro, I. J. Biol. Chem. (2000)
- Hypoxia-induced switches of myosin heavy chain iso-gene expression in rat heart. Razeghi, P., Essop, M.F., Huss, J.M., Abbasi, S., Manga, N., Taegtmeyer, H. Biochem. Biophys. Res. Commun. (2003)
- The different cardiac expression of the type 2 iodothyronine deiodinase gene between human and rat is related to the differential response of the Dio2 genes to Nkx-2.5 and GATA-4 transcription factors. Dentice, M., Morisco, C., Vitale, M., Rossi, G., Fenzi, G., Salvatore, D. Mol. Endocrinol. (2003)
- Reprogramming of gene expression in cultured cardiomyocytes and in explanted hearts by the myosin ATPase inhibitor butanedione monoxime. Thum, T., Borlak, J. Transplantation (2001)
- Regulation of DHP receptor expression by elements in the 5'-flanking sequence. Liu, L., Fan, Q.I., El-Zaru, M.R., Vanderpool, K., Hines, R.N., Marsh, J.D. Am. J. Physiol. Heart Circ. Physiol. (2000)
- Endothelin-converting enzyme-1 (ECE-1) is a downstream target of the homeobox transcription factor Nkx2-5. Funke-Kaiser, H., Lemmer, J., Langsdorff, C.V., Thomas, A., Kovacevic, S.D., Strasdat, M., Behrouzi, T., Zollmann, F.S., Paul, M., Orzechowski, H.D. FASEB J. (2003)
- Molecular mechanism of cardiac hypertrophy and development. Komuro, I. Jpn. Circ. J. (2001)
- Stem cell differentiation requires a paracrine pathway in the heart. Behfar, A., Zingman, L.V., Hodgson, D.M., Rauzier, J.M., Kane, G.C., Terzic, A., Pucéat, M. FASEB J. (2002)