Your search matched a total of 31 documents. Results 1 - 10.
Homo sapiens
Gene: ... ) abrogated SH2D1A binding to all four receptors. Association of the X- linked lymphoproliferative disease... amino acid with all known missense mutations in the SAP- encoding SH2D1A gene, including those of 4...Disease relevance of SH2D1A Thus, SH2D1A can affect multiple intracellular signaling pathways... / Synonyms: SAP/SH2D1A
Mus musculus
Gene: ... Disease relevance of Sh2d1a The primary manifestation of X- linked lymphoproliferative syndrome...( SAP ), is an excessive T cell response upon EBV infection. High impact information on Sh2d1a While evaluating the abnormalities in alphaGC- induced immune responses, we observed that Sh2d1a -/- animals lacked...
MeSH term: ... , and in the cardiovascular and immune systems. Gene context of Immune System SH2D1A is expressed in many tissues involved...
MeSH term: ... Disease relevance of Herpesvirus 4, Human Further analyses of the SAP/ SH2D1A gene in XLP patients have made it clear that the development of dys- gammaglobulinemia and B cell lymphoma can occur without..., preliminary results of virus infections of a mouse in which the SAP/ SH2D1A gene has been disrupted suggest...
MeSH term: ... the abnormalities in alphaGC- induced immune responses, we observed that Sh2d1a -/- animals lacked NKT cells... demonstrate that p53 is required for radiation- induced cell death in the thymus but is not necessary for all...( 6) normal thymus cells per ml. The thymus glands of all patients with CID and ADA deficiency who...
MeSH term: ... of the SH2D1A protein will probably provide new insights into the pathogenesis of severe infectious...
MeSH term: ... syndrome by sequencing the genomic SAP/ SH2D1A/ DSHP and perforin genes. Analytical, diagnostic... the course of several human inherited immune disorders, all of them resulting from molecular defects...
MeSH term: ... during convalescence, suggesting that SH2D1A protein is not directly responsible for control of EBV... the faeces or cerebrospinal fluid of all seven of the patients sampled, and serum antibody titres against EV33 were significantly elevated in the convalescence phase sera in all cases. Nonsteroidal anti...
Homo sapiens
Gene: ... transduction is controlled by SAP/ SH2D1A, the gene that is aberrant in X- linked lymphoproliferative disease.... The conditioning regimen consisted of busulfan and cyclophosphamide for all patients plus etoposide for patients...
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Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann







