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MeSH Review

Lymphohistiocytosis, Hemophagocytic

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Analytical, diagnostic and therapeutic context of Lymphohistiocytosis, Hemophagocytic


  1. The acute lupus hemophagocytic syndrome. Wong, K.F., Hui, P.K., Chan, J.K., Chan, Y.W., Ha, S.Y. Ann. Intern. Med. (1991) [Pubmed]
  2. Epstein-Barr virus LMP1 inhibits the expression of SAP gene and upregulates Th1 cytokines in the pathogenesis of hemophagocytic syndrome. Chuang, H.C., Lay, J.D., Hsieh, W.C., Wang, H.C., Chang, Y., Chuang, S.E., Su, I.J. Blood (2005) [Pubmed]
  3. Peripheral T-cell lymphoma associated with hemophagocytic syndrome and hemophagocytic lymphohistiocytosis of children: do they share something? Aricò, M. Blood (1990) [Pubmed]
  4. Parvovirus B19-associated hemophagocytic syndrome. Boruchoff, S.E., Woda, B.A., Pihan, G.A., Durbin, W.A., Burstein, D., Blacklow, N.R. Arch. Intern. Med. (1990) [Pubmed]
  5. Differential cellular susceptibility to Epstein-Barr virus infection in a patient with X-linked lymphoproliferative disease. Okano, M., Thiele, G.M., Gross, T.G., Davis, J.R., Purtilo, D.T. J. Med. Virol. (1990) [Pubmed]
  6. Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). Feldmann, J., Callebaut, I., Raposo, G., Certain, S., Bacq, D., Dumont, C., Lambert, N., Ouachée-Chardin, M., Chedeville, G., Tamary, H., Minard-Colin, V., Vilmer, E., Blanche, S., Le Deist, F., Fischer, A., de Saint Basile, G. Cell (2003) [Pubmed]
  7. Evidence that Griscelli syndrome with neurological involvement is caused by mutations in RAB27A, not MYO5A. Anikster, Y., Huizing, M., Anderson, P.D., Fitzpatrick, D.L., Klar, A., Gross-Kieselstein, E., Berkun, Y., Shazberg, G., Gahl, W.A., Hurvitz, H. Am. J. Hum. Genet. (2002) [Pubmed]
  8. Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome. Mazodier, K., Marin, V., Novick, D., Farnarier, C., Robitail, S., Schleinitz, N., Veit, V., Paul, P., Rubinstein, M., Dinarello, C.A., Harlé, J.R., Kaplanski, G. Blood (2005) [Pubmed]
  9. Linkage of familial hemophagocytic lymphohistiocytosis (FHL) type-4 to chromosome 6q24 and identification of mutations in syntaxin 11. zur Stadt, U., Schmidt, S., Kasper, B., Beutel, K., Diler, A.S., Henter, J.I., Kabisch, H., Schneppenheim, R., Nürnberg, P., Janka, G., Hennies, H.C. Hum. Mol. Genet. (2005) [Pubmed]
  10. Central nervous system involvement in the erythrophagocytic disorders of infancy: the role of cerebrospinal fluid neopterins in their differential diagnosis and clinical management. Howells, D.W., Strobel, S., Smith, I., Levinsky, R.J., Hyland, K. Pediatr. Res. (1990) [Pubmed]
  11. Subcutaneous panniculitic T-cell lymphoma in children: response to combination therapy with cyclosporine and chemotherapy. Shani-Adir, A., Lucky, A.W., Prendiville, J., Murphy, S., Passo, M., Huang, F.S., Paller, A.S. J. Am. Acad. Dermatol. (2004) [Pubmed]
  12. Pancytopenia secondary to hemophagocytic syndrome in rheumatoid arthritis treated with methotrexate and sulfasalazine. Sibilia, J., Javier, R.M., Albert, A., Cazenave, J.P., Kuntz, J.L. J. Rheumatol. (1998) [Pubmed]
  13. Prolonged resolution of hemophagocytic lymphohistiocytosis following myeloablative chemotherapy and subsequent autologous peripheral blood stem cell transplantation. Ohga, S., Nomura, A., Kai, T., Matsuzaki, A., Inaba, S., Suda, M., Ueda, K. Bone Marrow Transplant. (1997) [Pubmed]
  14. Effective control of infection-associated hemophagocytic syndrome with chloroquine. Gong, X.S. J. Pediatr. Hematol. Oncol. (2002) [Pubmed]
  15. Hemophagocytic lymphohistiocytosis: a hemophagocytic syndrome. Favara, B.E. Seminars in diagnostic pathology. (1992) [Pubmed]
  16. Effective anti-viral therapy for hemophagocytic syndrome associated with B-cell lymphoma. Gomyo, H., Shimoyama, M., Minagawa, K., Yakushijin, K., Urahama, N., Okamura, A., Yamamoto, K., Ito, M., Chihara, K., Matsui, T. Leuk. Lymphoma (2003) [Pubmed]
  17. Defective cytotoxic granule-mediated cell death pathway impairs T lymphocyte homeostasis. de Saint Basile, G., Fischer, A. Current opinion in rheumatology. (2003) [Pubmed]
  18. Clinical significance of simultaneous determination of serum soluble transferrin receptor, soluble Fas, soluble Fas ligand, hepatocyte growth factor and interleukin 18 levels in a patient with hemophagocytic syndrome. Takubo, T., Kumura, T., Nishiki, S., Kinoshita, Y., Koh, K., Ohta, K., Yamane, T., Hino, M., Kamitani, T., Tatsumi, N. Acta Haematol. (2000) [Pubmed]
  19. Soluble hemoglobin-haptoglobin scavenger receptor CD163 as a lineage-specific marker in the reactive hemophagocytic syndrome. Schaer, D.J., Schleiffenbaum, B., Kurrer, M., Imhof, A., Bächli, E., Fehr, J., Moller, H.J., Moestrup, S.K., Schaffner, A. Eur. J. Haematol. (2005) [Pubmed]
  20. Inflammatory cytokines in virus-associated hemophagocytic syndrome. Interferon-gamma as a sensitive indicator of disease activity. Ohga, S., Matsuzaki, A., Nishizaki, M., Nagashima, T., Kai, T., Suda, M., Ueda, K. The American journal of pediatric hematology/oncology. (1993) [Pubmed]
  21. Munc13-4 is an effector of rab27a and controls secretion of lysosomes in hematopoietic cells. Neeft, M., Wieffer, M., de Jong, A.S., Negroiu, G., Metz, C.H., van Loon, A., Griffith, J., Krijgsveld, J., Wulffraat, N., Koch, H., Heck, A.J., Brose, N., Kleijmeer, M., van der Sluijs, P. Mol. Biol. Cell (2005) [Pubmed]
  22. MIP-1alpha expression in tissues from patients with hemophagocytic syndrome. Teruya-Feldstein, J., Setsuda, J., Yao, X., Kingma, D.W., Straus, S., Tosato, G., Jaffe, E.S. Lab. Invest. (1999) [Pubmed]
  23. No mutations of SAP/SH2D1A/DSHP and perforin genes in patients with Epstein-Barr virus-associated hemophagocytic syndrome in Japan. Ma, X., Okamura, A., Yosioka, M., Ishiguro, N., Kikuta, H., Kobayashi, K. J. Med. Virol. (2001) [Pubmed]
  24. Allogeneic hematopoietic stem cell transplantation for patients with hemophagocytic syndrome (HPS) in Japan. Imashuku, S., Hibi, S., Todo, S., Sako, M., Inoue, M., Kawa, K., Koike, K., Iwai, A., Tsuchiya, S., Akiyama, Y., Kotani, T., Kawamura, Y., Hirosawa, M., Hasegawa, D., Kosaka, Y., Yamaguchi, H., Ishii, E., Kato, K., Ishii, M., Kigasawa, H. Bone Marrow Transplant. (1999) [Pubmed]
  25. Latency pattern of Epstein-Barr virus and methylation status in Epstein-Barr virus-associated hemophagocytic syndrome. Yoshioka, M., Kikuta, H., Ishiguro, N., Endo, R., Kobayashi, K. J. Med. Virol. (2003) [Pubmed]
  26. Hemophagocytic lymphohistiocytosis after chemotherapy for multiple myeloma. Terrovitis, J.V., Matsouka, C., Anagnostopoulos, A., Anastasiou-Nana, M.I., Dimopoulos, A.M. Clinical lymphoma. (2004) [Pubmed]
  27. Virus-associated hemophagocytic syndrome in an international traveler as a differential diagnosis of SARS. Ishii, H., Asai, S., Suzuki, T., Eguchi, K., Miyachi, H. Intern. Med. (2005) [Pubmed]
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