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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 187 documents. Results 1 - 10.

Homo sapiens
Gene: ... Disease relevance of SMAD3 Isoprenoid- mediated control of SMAD3 expression in a cultured model... of this gene were found in four of the 12 carcinomas; no SMAD2 or SMAD3 inactivating genomic alterations were found. SMAD3 is a transcription factor that mediates TGF- beta1 signaling and is known to be important... / Synonyms: SMAD 3; Smad3; hSMAD3
Mus musculus
Gene: ... of Smad3 in the context of a Smad2- deficient epiblast results in a failure to specify all axial midline... in an inhibition of the AP- 1- driven induction of the PPARbeta/ delta promoter. CONCLUSION: Smad 3 binds all three...Disease relevance of Smad3 Between 4 and 6 months of age, the Smad3 mutant mice become moribund... / Synonyms: SMAD 3; Smad 3
Rattus norvegicus
Gene: ... Disease relevance of Smad3 Nuclear localization of Smad2/ Smad3 indicated that the TGF- beta... of Smad2 and Smad3 in an in vivo animal model of lung fibrosis induced by bleomycin. We found that the expression of Smad3 was regulated in lungs during bleomycin- induced pulmonary fibrosis. To characterize... / Synonyms: SMAD 3; Smad 3
Danio rerio
Gene: ... High impact information on smad3a Cloning and characterization of zebrafish smad2, smad3 and smad4.... / Synonyms: smad3
Gallus gallus
Gene: ... Disease relevance of SMAD3 Furthermore, infection with a Smad 3- expressing retrovirus mimicked... culture. Psychiatry related information on SMAD3 Smad3- mediated TGFbeta activity promotes cell- cycle... of neurogenic factors and the cyclin- dependent- kinase- inhibitor p27( kip1). High impact information on SMAD3...
Danio rerio
Gene: ... High impact information on smad3b Although mammalian Smad3 was shown to inhibit expression of the organizer- specific genes goosecoid, zebrafish smad3b activates organizer genes such as goosecoid....
Homo sapiens
Gene: ... cells, all of the Ski protein was found in Smad3- containing complexes that accumulated in the nucleus... inhibitor, increased expression of beta- catenin and attenuated TGF- beta1- dependent Smad3 signaling...- inducible genes. Both Smad2 and Smad3 were phosphorylated in response to TGF- beta1 beginning at 5 minutes...
MeSH term: ... - alpha accelerate wound healing, but treatment effects are often modest. Mice lacking Smad3 show...
MeSH term: ... , and that Smad2 and Smad3 have distinct functions in this endogenous control of differentiation. Stromelysin- 1...
MeSH term: ... , these studies suggest that the TGF- beta signal transducer, Smad3, is required for the development... We found that vascular permeability in the tracheas of all rats was normal in the absence... but is not responsible for all Wnt functions there. Similarly, addition of hypotonic PBS to mouse trachea in vivo...


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