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Chemical Compound Review

Pentamethonum     trimethyl-(5- trimethylammoniopentyl)azanium

Synonyms: Pentamethonium, AC1L1W8E, 2365-25-5, UNII-521DS2D2HB, 541-20-8 (dibromide), ...
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Disease relevance of NSC148343

  • Atropine caused a dose-dependent (10(-7) M, 10(-6) M) decrease in the maximal response (non-competitive antagonism), while the ganglion blocker pentamethonium (10(-4) M) was without effect [1].

High impact information on NSC148343


  1. Dopamine, noradrenaline and isoprenaline: secretory and electrophysiological effects in vitro on mouse pancreas. Berger, Z., Laugier, R. J. Physiol. (Lond.) (1986) [Pubmed]
  2. The role of nicotinic receptors in dog pancreatic exocrine secretion. Devaux, M.A., Diaz, G.R., Kubota, K., Magee, D.F., Sarles, H. Br. J. Pharmacol. (1983) [Pubmed]
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