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MeSH Review

Ganglia, Autonomic

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Disease relevance of Ganglia, Autonomic


High impact information on Ganglia, Autonomic


Biological context of Ganglia, Autonomic


Anatomical context of Ganglia, Autonomic


Associations of Ganglia, Autonomic with chemical compounds

  • Immunohistochemical demonstration of choline acetyltransferase-immunoreactive preganglionic nerve fibers in guinea pig autonomic ganglia [20].
  • Various lines of evidence suggest that the high affinity agonist-binding sites in brain correspond to nicotinic cholinergic receptors similar to those found at autonomic ganglia; BTX-binding sites may also serve as receptors for nicotine and are possibly related to neuromuscular nicotinic cholinoceptors [21].
  • The ganglionic antagonist, trimethaphan, which impairs neurotransmission across parasympathetic and sympathetic autonomic ganglia, or atropine or saline was given intravenously during the first 15 min after ingestion of a standard meal (350 kcal) [22].
  • Vasodepression produced by blocking autonomic ganglia pharmacologically with pentolinium was also more pronounced in DOCA hypertensive rats than in normotensive controls [23].
  • Alterations in the extrinsic innervation of the alimentary tract and in various sympathetic autonomic ganglia were examined using quantitative ultrastructural and biochemical methods in streptozotocin diabetic rats maintained without treatment for 9-15 months [24].

Gene context of Ganglia, Autonomic


Analytical, diagnostic and therapeutic context of Ganglia, Autonomic


  1. Effects of aldose reductase inhibitor sorbinil on neuroaxonal dystrophy and levels of myo-inositol and sorbitol in sympathetic autonomic ganglia of streptozocin-induced diabetic rats. Schmidt, R.E., Plurad, S.B., Sherman, W.R., Williamson, J.R., Tilton, R.G. Diabetes (1989) [Pubmed]
  2. K+ channel expression in primary cell cultures mediated by vaccinia virus. Karschin, A., Aiyar, J., Gouin, A., Davidson, N., Lester, H.A. FEBS Lett. (1991) [Pubmed]
  3. Hypotensive effect of the methanolic extract of Mimusops elengi in normotensive rats. Dar, A., Behbahanian, S., Malik, A., Jahan, N. Phytomedicine (1999) [Pubmed]
  4. Gastrointestinal manifestations of Niemann-Pick disease. Dinari, G., Rosenbach, Y., Grunebaum, M., Zahavi, I., Alpert, G., Nitzan, M. Enzyme (1980) [Pubmed]
  5. Autoantibodies to ganglionic acetylcholine receptors in autoimmune autonomic neuropathies. Vernino, S., Low, P.A., Fealey, R.D., Stewart, J.D., Farrugia, G., Lennon, V.A. N. Engl. J. Med. (2000) [Pubmed]
  6. Neuronal dopamine receptors on autonomic ganglia and sympathetic nerves and dopamine receptors in the gastrointestinal system. Willems, J.L., Buylaert, W.A., Lefebvre, R.A., Bogaert, M.G. Pharmacol. Rev. (1985) [Pubmed]
  7. Substance P: a putative sensory transmitter in mammalian autonomic ganglia. Jiang, Z., Dun, N.J., Karczmar, A.G. Science (1982) [Pubmed]
  8. Defects in sensory and autonomic ganglia and absence of locus coeruleus in mice deficient for the homeobox gene Phox2a. Morin, X., Cremer, H., Hirsch, M.R., Kapur, R.P., Goridis, C., Brunet, J.F. Neuron (1997) [Pubmed]
  9. Expression and regulation of the neuropeptide Y Y2 receptor in sensory and autonomic ganglia. Zhang, X., Shi, T., Holmberg, K., Landry, M., Huang, W., Xiao, H., Ju, G., Hökfelt, T. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  10. Enkephalins presynaptically inhibit cholinergic transmission in sympathetic ganglia. Konishi, S., Tsunoo, A., Otsuka, M. Nature (1979) [Pubmed]
  11. Low intensity spinal cord stimulation may induce cutaneous vasodilation via CGRP release. Tanaka, S., Barron, K.W., Chandler, M.J., Linderoth, B., Foreman, R.D. Brain Res. (2001) [Pubmed]
  12. Diverse vascular responses to serotonin in the conscious rabbit: effects of serotonin antagonists on renal artery spasm. Wright, C.E., Angus, J.A. J. Cardiovasc. Pharmacol. (1987) [Pubmed]
  13. Support of arterial blood pressure by major pressor systems in conscious dogs. Brand, P.H., Metting, P.J., Britton, S.L. Am. J. Physiol. (1988) [Pubmed]
  14. Nitric oxide release and long term potentiation at synapses in autonomic ganglia. Bennett, M.R. Gen. Pharmacol. (1994) [Pubmed]
  15. Substance P modulation of acetylcholine-induced currents in embryonic chicken sympathetic and ciliary ganglion neurons. Role, L.W. Proc. Natl. Acad. Sci. U.S.A. (1984) [Pubmed]
  16. Development of bone morphogenetic protein receptors in the nervous system and possible roles in regulating trkC expression. Zhang, D., Mehler, M.F., Song, Q., Kessler, J.A. J. Neurosci. (1998) [Pubmed]
  17. Expression of aminopeptidase N (CD13) in mesenchymal tumors. Mechtersheimer, G., Möller, P. Am. J. Pathol. (1990) [Pubmed]
  18. Structure of the m1 muscarinic acetylcholine receptor gene and its promoter. Pepitoni, S., Wood, I.C., Buckley, N.J. J. Biol. Chem. (1997) [Pubmed]
  19. The acetylcholine receptor of the neuromuscular junction recognizes mecamylamine as a noncompetitive antagonist. Varanda, W.A., Aracava, Y., Sherby, S.M., VanMeter, W.G., Eldefrawi, M.E., Albuquerque, E.X. Mol. Pharmacol. (1985) [Pubmed]
  20. Immunohistochemical demonstration of choline acetyltransferase-immunoreactive preganglionic nerve fibers in guinea pig autonomic ganglia. Lindh, B., Staines, W., Hökfelt, T., Terenius, L., Salvaterra, P.M. Proc. Natl. Acad. Sci. U.S.A. (1986) [Pubmed]
  21. Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125I]-alpha-bungarotoxin. Clarke, P.B., Schwartz, R.D., Paul, S.M., Pert, C.B., Pert, A. J. Neurosci. (1985) [Pubmed]
  22. The cephalic insulin response to meal ingestion in humans is dependent on both cholinergic and noncholinergic mechanisms and is important for postprandial glycemia. Ahrén, B., Holst, J.J. Diabetes (2001) [Pubmed]
  23. Augmented sympathetic nerve activity and pressor responsiveness in DOCA hypertensive rats. Takeda, K., Buñag, R.D. Hypertension (1980) [Pubmed]
  24. Ultrastructural and biochemical characterization of autonomic neuropathy in rats with chronic streptozotocin diabetes. Schmidt, R.E., Plurad, S.B. J. Neuropathol. Exp. Neurol. (1986) [Pubmed]
  25. CYP2J subfamily cytochrome P450s in the gastrointestinal tract: expression, localization, and potential functional significance. Zeldin, D.C., Foley, J., Goldsworthy, S.M., Cook, M.E., Boyle, J.E., Ma, J., Moomaw, C.R., Tomer, K.B., Steenbergen, C., Wu, S. Mol. Pharmacol. (1997) [Pubmed]
  26. Differential expression of estrogen receptors alpha and beta in adult rat accessory sex glands and lower urinary tract. Mäkelä, S., Strauss, L., Kuiper, G., Valve, E., Salmi, S., Santti, R., Gustafsson, J.A. Mol. Cell. Endocrinol. (2000) [Pubmed]
  27. The candidate neuroprotective agent artemin induces autonomic neural dysplasia without preventing peripheral nerve dysfunction. Bolon, B., Jing, S., Asuncion, F., Scully, S., Pisegna, M., Van, G.Y., Hu, Z., Yu, Y.B., Min, H., Wild, K., Rosenfeld, R.D., Tarpley, J., Carnahan, J., Duryea, D., Hill, D., Kaufman, S., Yan, X.Q., Juan, T., Christensen, K., McCabe, J., Simonet, W.S. Toxicologic pathology. (2004) [Pubmed]
  28. MASH1 activates expression of the paired homeodomain transcription factor Phox2a, and couples pan-neuronal and subtype-specific components of autonomic neuronal identity. Lo, L., Tiveron, M.C., Anderson, D.J. Development (1998) [Pubmed]
  29. Expression of HLA-A,B,C, beta 2-microglobulin (beta 2m), HLA-DR, -DP, -DQ and of HLA-D-associated invariant chain (Ii) in soft-tissue tumors. Mechtersheimer, G., Staudter, M., Majdic, O., Dörken, B., Moldenhauer, G., Möller, P. Int. J. Cancer (1990) [Pubmed]
  30. Evidence for a renomedullary vasodepressor system in rabbits and dogs. Christy, I.J., Woods, R.L., Courneya, C.A., Denton, K.M., Anderson, W.P. Hypertension (1991) [Pubmed]
  31. Mechanism of tracheal constriction by succinylcholine. Koga, Y., Downes, H., Leon, D.A., Hirshman, C.A. Anesthesiology (1981) [Pubmed]
  32. The role of nicotinic receptors in dog pancreatic exocrine secretion. Devaux, M.A., Diaz, G.R., Kubota, K., Magee, D.F., Sarles, H. Br. J. Pharmacol. (1983) [Pubmed]
  33. Serotonin immunoreactivity in the autonomic intrapulmonary ganglia of the fetal sheep. Balaguer, L., Romano, J., Ruiz-Pesini, P. Neurosci. Lett. (1991) [Pubmed]
  34. Energy expenditure by intravenous administration of glucagon-like peptide-1 mediated by the lower brainstem and sympathoadrenal system. Osaka, T., Endo, M., Yamakawa, M., Inoue, S. Peptides (2005) [Pubmed]
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