Disease relevance of methyldisulfanylmethane

• Separate acute administrations of ammonia, dimethyldisulfide, and octanoic acid induced lethargy, convulsions in the case of the first two, and coma with visual-evoked potential patterns that never resembled the evoked potentials recorded in hepatic coma [1].

High impact information on methyldisulfanylmethane

• Visual evoked potentials in encephalopathy induced by galactosamine, ammonia, dimethyldisulfide, and octanoic acid [1].
• The monoenoic fatty acids from whole cells were converted to methyl esters and then to DMDS adducts and analyzed by capillary gas chromatography-mass spectrometry [2].
• Volatile sulfur-containing compounds (ie, methanethiol, carbon disulfide, dimethyldisulfide, and sulfur dioxide) were detected by gas chromatography and mass spectrometry in 8 of 12 water samples from the RO unit and in 0 of 28 samples from other areas (P < .001) [3].
• Pups sniffed in response to the highest concentrations of DMDS, exhibiting a lower olfactory threshold when awake [4].
• Greatest dimethyl disulphide (DMDS) and DMTS production (> 3000 ng L-1 DMTS) occurred in the reactors when supplied with methane thio-containing compounds, such as methionine, S-methyl cysteine and methyl-3-(methylmercapto)-propionate [5].

Analytical, diagnostic and therapeutic context of methyldisulfanylmethane

• The double bond positions were determined by gas chromatography/mass spectrometry on the corresponding dimethyl-disulfide adducts and the double bond stereochemistry was ascertained by gas chromatography/Fourier transform infrared spectroscopy [6].

References