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Chemical Compound Review:

ethanyl ethane

Synonyms: Z-ethyl, Ethyl radical, ethane radical, CHEBI:62801, KST-1A2584, ...

Ishibashi, M. et al., Taffe, B.G. et al., Kennedy, C.H. et al., Sugiyama, K. et al., Li, Q. et al.

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High impact information on ethane

In the presence of the spin trap alpha-(4-pyridyl 1-oxide)-N-tert-butylnitrone (4-POBN), this radical was detected as the 4-POBN/ethyl radical adduct by electron paramagnetic resonance spectroscopy [1].
Spin trapping of the alkyl radicals with 2-methyl-2-nitrosopropane led to the identification of methyl and ethyl radical adducts following both tert-butyl hydroperoxide and cumene hydroperoxide exposures [2].
Thus the inactivation of HRP appears to depend on the formation of an ethyl radical, which presumably reacts with the heme in the active site of the enzyme [3].
The staggered ethyl radical-like structure lies only 0.1 kcal/mol higher in energy, with a Cu-Cu distance shorter by only approximately 0.001 A [4].
The major fragmentations were directed by the DES group, and other fragmentations common to the prostanoid derivatives were losses of an ethyl radical at the silicon atom, C5H11 hydrocarbon fragment, diethylhydrogensilanol and C15-C20 hydrocarbon fragment [5].

References

A reexamination of the cytochrome P-450-catalyzed free radical production from a dihydropyridine. Evidence of trace transition metal catalysis. Kennedy, C.H., Mason, R.P. J. Biol. Chem. (1990) [Pubmed]
Generation of free radicals from organic hydroperoxide tumor promoters in isolated mouse keratinocytes. Formation of alkyl and alkoxyl radicals from tert-butyl hydroperoxide and cumene hydroperoxide. Taffe, B.G., Takahashi, N., Kensler, T.W., Mason, R.P. J. Biol. Chem. (1987) [Pubmed]
pH-dependent one- and two-electron oxidation of 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine catalyzed by horseradish peroxidase. Sugiyama, K., Correia, M.A., Thummel, K.E., Nagata, K., Darbyshire, J.F., Osawa, Y., Gillette, J.R. Chem. Res. Toxicol. (1994) [Pubmed]
Binuclear homoleptic copper carbonyls Cu(2)(CO)(x) (x = 1-6): remarkable structures contrasting metal-metal multiple bonding with low-dimensional copper bonding manifolds. Li, Q., Liu, Y., Xie, Y., King, R.B., Schaefer, H.F. Inorganic chemistry. (2001) [Pubmed]
Diethylhydrogensilyl-cyclic diethylsilylene derivatives in gas chromatography-mass spectrometry of prostanoids. III. F alpha-prostaglandins and thromboxane B2 derivatives. Ishibashi, M., Watanabe, K., Yamashita, K., Miyazaki, H., Krolik, S. J. Chromatogr. (1987) [Pubmed]

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