Disease relevance of Cetylene

• 1. The induction of intracytoplasmic membranes was demonstrated to occur in Acinetobacter sp. when grown on hexadecane, heptadecane, and hexadec-1-ene [1].

High impact information on Cetylene

• The biotransformation of 1-hexadecene to carcinogenic 1,2-epoxyhexadecane by hepatic microsomes [2].
• Intercalation of 50 mol% cholesterol into DPPC bilayers, which induces a phase transition to a liquid-crystalline phase, substantially increases the apparent barrier domain hydrophobicity relative to gel-phase bilayers to a nonhydrogen bonding, hydrocarbonlike environment resembling hexadecene [3].
• The inhibition by IC of the microsomal cholesterol alpha-epoxide hydrolysis was competitive, but no significant inhibition of the enzyme activity was observed by the typical microsomal xenobiotic substrates, hexadecene oxide and benzo[a]pyrene 4,5-oxide [4].
• The lipid was subjected to mild alkaline hydrolysis, and the structures of the hydrolysis products were identified by infrared spectra, mass and nuclear magnetic resonance spectrometries, as fatty acids and hexadecane-, hexadecene- and tetradecanethioic S-acids [5].

Analytical, diagnostic and therapeutic context of Cetylene

• 2 compounds encountered in modern electron microscopy technique, 1-hexadecene (1-HD) and 2-hydroxyethyl acrylate (2-HEA), which elicit allergic and/or toxic reactions in laboratory workers, were tested for their penetration through the 4H Glove material 1-HD has not to our knowledge been tested on any glove material [6].

References