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Chemical Compound Review:

aminomethyl methanamine

Synonyms: CH2NH2, AC1L3K8T, 35430-17-2, Aminomethyl radical, Methylene, 1-amino-

Lanzafame, A. et al., Ebadi, M. et al., Elslager, E.F. et al., Mohanty, S.K. et al., Mascavage, L.M. et al., et al.

Mohanty, Radotra, Banerjee,

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High impact information on methanamine

The requisite N-methylarylmethanamines (21-32) were prepared by the hydrogenation over Pt/C of the corresponding arylcarboxaldehyde in the presence of methanamine [1].
On the Surface-Catalyzed Reaction between the Gases 2,2-Dimethylpropanal and Methanamine. Formation of Active-Site Imines [2].
Investigation of the interaction of a putative allosteric modulator, N-(2,3-diphenyl-1,2,4-thiadiazole-5-(2H)-ylidene) methanamine hydrobromide (SCH-202676), with M1 muscarinic acetylcholine receptors [3].
The interaction between a novel G protein-coupled receptor modulator, N-(2,3-diphenyl-1,2,4-thiadiazole-5-(2H)-ylidene) methanamine hydrobromide (SCH-202676), and the M(1) muscarinic acetylcholine receptor (mAChR) was investigated [3].
Structure-activity relationships of these analogues indicated that the presence of a CHO in position 4 of the pyridine ring was essential, since its conversion to CH2NH2 or CH2OH abolished activity [4].

Anatomical context of methanamine

Silver methanamine stain enhanced the rounded, helmet or cleft forms of sporozoites [5].

Analytical, diagnostic and therapeutic context of methanamine

The results of immunohistochemistry to label the NFT (Tau) and SP (beta-amyloid) were comparable to the Bielchowsky's modified silver methanamine method [6].

References

Folate antagonists. 18. Synthesis and antimalarial effects of N6-(arylmethyl)-N6-methyl-2,4,6-pteridinetriamines and related N6,N6-disubstituted 2,4,6-pteridinetriamines. Elslager, E.F., Johnson, J.L., Werbel, L.M. J. Med. Chem. (1981) [Pubmed]
On the Surface-Catalyzed Reaction between the Gases 2,2-Dimethylpropanal and Methanamine. Formation of Active-Site Imines. Mascavage, L.M., Sonnet, P.E., Dalton, D.R. J. Org. Chem. (2006) [Pubmed]
Investigation of the interaction of a putative allosteric modulator, N-(2,3-diphenyl-1,2,4-thiadiazole-5-(2H)-ylidene) methanamine hydrobromide (SCH-202676), with M1 muscarinic acetylcholine receptors. Lanzafame, A., Christopoulos, A. J. Pharmacol. Exp. Ther. (2004) [Pubmed]
Convulsant activity of pyridoxal sulphate and phosphonoethyl pyridoxal: antagonism by GABA and its synthetic analogues. Ebadi, M., Metzler, D.E., Christenson, W.R. Neuropharmacology (1983) [Pubmed]
Diagnosis of Pneumocystis pneumonia by bronchoalveolar lavage cytology: experience at a tertiary care centre in India. Dahiya, S., Mathur, S.R., Iyer, V.K., Kapila, K., Verma, K. The Indian journal of chest diseases & allied sciences. (2005) [Pubmed]
Aging changes in the human brain: a histochemical and immunohistochemical study. Mohanty, S.K., Radotra, B.D., Banerjee, A.K. Neuropathology : official journal of the Japanese Society of Neuropathology. (2004) [Pubmed]

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