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Chemical Compound Review:

Methelute trimethyl-phenyl-azanium hydroxide

Synonyms: PTAH, SureCN35582, AG-E-38637, ACMC-209skr, ANW-41305, ...

This record was replaced with 15914.

Midha, K.K. et al., Förster, H.J. et al., Brondz, I. et al., Kelly, R.C. et al., Davis, H.L. et al., et al.

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High impact information on Phenyltrimethylammonium

Solvent suppression of the decomposition of phenobarbital during on-column methylation with trimethylanilinium hydroxide [1].
The structures of the methylated clonidine derivatives formed by on column methylation with trimethylanilinium hydroxide are revised [2].

Biological context of Phenyltrimethylammonium

The N,N-dimethyl derivatives of the compounds are prepared by "oncolumn" methylation with 50% Methelute [3].

Associations of Phenyltrimethylammonium with other chemical compounds

After extraction, the drug, the metabolite, and the internal standard, 5-(p-methylphenyl)-5-phenylhydantoin, are measured by GLC with flame-ionization detection as their respective methyl derivatives following flash-heater methylation with trimethylanilinium hydroxide [4].
The on column methylation of clonidine and p-hydroxyclonidine with trimethylanilinium hydroxide [2].
Gas chromatography of uracil herbicides by on-column methylation with trimethylanilinium hydroxide [5].

Analytical, diagnostic and therapeutic context of Phenyltrimethylammonium

The fatty acids were identified and quantified by gas chromatography and gas chromatography-mass spectrometry after intra-injector derivation with trimethylanilinium hydroxide [6].

References

Solvent suppression of the decomposition of phenobarbital during on-column methylation with trimethylanilinium hydroxide. Kelly, R.C., Valentour, J.C., Sunshine, I. J. Chromatogr. (1977) [Pubmed]
The on column methylation of clonidine and p-hydroxyclonidine with trimethylanilinium hydroxide. Förster, H.J., Stähle, H. Biomed. Mass Spectrom. (1978) [Pubmed]
Improved method for the simultaneous determination of phenobarbital, primidone and diphenylhydantoin in patient's serum by gas-liquid chromatography. Davis, H.L., Falk, K.J., Bailey, D.G. J. Chromatogr. (1975) [Pubmed]
Sensitive GLC procedure simultaneous determination of phenytoin and its major metabolite from plasma following single doses of phenytoin. Midha, K.K., McGilveray, I.J., Wilson, D.L. Journal of pharmaceutical sciences. (1976) [Pubmed]
Gas chromatography of uracil herbicides by on-column methylation with trimethylanilinium hydroxide. Ogierman, L. Journal - Association of Official Analytical Chemists. (1986) [Pubmed]
Intra-injector methylation of free fatty acids from aerobically and anaerobically cultured Actinobacillus actinomycetemcomitans and Haemophilus aphrophilus. Brondz, I., Olsen, I. J. Chromatogr. (1992) [Pubmed]

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