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Chemical Compound Review

CHEMBL115824     (2R,3R,4S,5R)-2-(5-amino- 2,7,9...

Synonyms: CHEBI:285657, AR-1E8103, AR-1E8104, PDSP1_001078, PDSP2_001062, ...
 
 
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Disease relevance of 1-Deaza-A

 

High impact information on 1-Deaza-A

References

  1. Improved synthesis and antitumor activity of 1-deazaadenosine. Cristalli, G., Franchetti, P., Grifantini, M., Vittori, S., Bordoni, T., Geroni, C. J. Med. Chem. (1987) [Pubmed]
  2. A pre-transition-state mimic of an enzyme: X-ray structure of adenosine deaminase with bound 1-deazaadenosine and zinc-activated water. Wilson, D.K., Quiocho, F.A. Biochemistry (1993) [Pubmed]
  3. ADA2 isoform of adenosine deaminase from pleural fluid. Andreasyan, N.A., Hairapetyan, H.L., Sargisova, Y.G., Mardanyan, S.S. FEBS Lett. (2005) [Pubmed]
  4. Binding thermodynamics of the transition state analogue coformycin and of the ground state analogue 1-deazaadenosine to bovine adenosine deaminase. Castro, C., Britt, B.M. J. Enzym. Inhib. (2001) [Pubmed]
  5. Inhibition of adenosine deaminase from several sources by deaza derivatives of adenosine and EHNA. Lupidi, G., Cristalli, G., Marmocchi, F., Riva, F., Grifantini, M. J. Enzym. Inhib. (1985) [Pubmed]
 
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