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MeSH Review


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Disease relevance of Hyperbilirubinemia


Psychiatry related information on Hyperbilirubinemia


High impact information on Hyperbilirubinemia


Chemical compound and disease context of Hyperbilirubinemia


Biological context of Hyperbilirubinemia


Anatomical context of Hyperbilirubinemia


Gene context of Hyperbilirubinemia


Analytical, diagnostic and therapeutic context of Hyperbilirubinemia


  1. Dual hereditary jaundice: simultaneous occurrence of mutations causing Gilbert's and Dubin-Johnson syndrome. Cebecauerova, D., Jirasek, T., Budisova, L., Mandys, V., Volf, V., Novotna, Z., Subhanova, I., Hrebicek, M., Elleder, M., Jirsa, M. Gastroenterology (2005) [Pubmed]
  2. Chronic persistent hepatitis and unconjugated hyperbilirubinemia. Felsher, B.F., Carpio, N.M. Gastroenterology (1979) [Pubmed]
  3. Stimulation of bilirubin formation in liver of newborn rats by fasting and glucagon. Thaler, M.M., Dawber, N.H. Gastroenterology (1977) [Pubmed]
  4. Lifelong elimination of hyperbilirubinemia in the Gunn rat with a single injection of helper-dependent adenoviral vector. Toietta, G., Mane, V.P., Norona, W.S., Finegold, M.J., Ng, P., McDonagh, A.F., Beaudet, A.L., Lee, B. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  5. Quantitative aspects of bilirubin metabolism for hematologists. Berlin, N.I., Berk, P.D. Blood (1981) [Pubmed]
  6. The critical period of Purkinje cell degeneration and cerebellar hypoplasia due to bilirubin. Takagishi, Y., Yamamura, H. Acta Neuropathol. (1987) [Pubmed]
  7. Phenobarbital prophylaxis for hyperbilirubinemia in preterm infants. A controlled study of bilirubin disappearance and infant behavior. Wallin, A., Boréus, L.O. Acta paediatrica Scandinavica. (1984) [Pubmed]
  8. Controlled trial of interleukin-2 infusions in patients infected with the human immunodeficiency virus. Kovacs, J.A., Vogel, S., Albert, J.M., Falloon, J., Davey, R.T., Walker, R.E., Polis, M.A., Spooner, K., Metcalf, J.A., Baseler, M., Fyfe, G., Lane, H.C. N. Engl. J. Med. (1996) [Pubmed]
  9. The clinical importance of a protein-bound fraction of serum bilirubin in patients with hyperbilirubinemia. Weiss, J.S., Gautam, A., Lauff, J.J., Sundberg, M.W., Jatlow, P., Boyer, J.L., Seligson, D. N. Engl. J. Med. (1983) [Pubmed]
  10. Artifactual lowering of serum creatinine levels in the presence of hyperbilirubinemia. Halstead, A.C., Nanji, A.A. JAMA (1984) [Pubmed]
  11. Propranolol and spurious hyperbilirubinemia. Belsey, R., Mueggler, P., Swanson, J.R. JAMA (1984) [Pubmed]
  12. Long-term administration of massive doses of Sn-protoporphyrin in anemic mutant mice (sphha/sphha). Sassa, S., Drummond, G.S., Bernstein, S.E., Kappas, A. J. Exp. Med. (1985) [Pubmed]
  13. An experimental model of postnatal jaundice in the suckling rat. Suppression of induced hyperbilirubinemia by Sn-protoporphyrin. Drummond, G.S., Kappas, A. J. Clin. Invest. (1984) [Pubmed]
  14. Two distinct mechanisms for bilirubin glucuronide transport by rat bile canalicular membrane vesicles. Demonstration of defective ATP-dependent transport in rats (TR-) with inherited conjugated hyperbilirubinemia. Nishida, T., Gatmaitan, Z., Roy-Chowdhry, J., Arias, I.M. J. Clin. Invest. (1992) [Pubmed]
  15. Ursodeoxycholic acid oral tolerance test in patients with constitutional hyperbilirubinemias and effect of phenobarbital. Ohkubo, H., Okuda, K., Iida, S., Makino, I. Gastroenterology (1981) [Pubmed]
  16. Ursodeoxycholic acid for the treatment of home parenteral nutrition-associated cholestasis. A case report. Lindor, K.D., Burnes, J. Gastroenterology (1991) [Pubmed]
  17. Serum primary bile acids in Gilbert's syndrome. Roda, A., Roda, E., Sama, C., Festi, D., Aldini, R., Morselli, A.M., Mazzella, G., Barbara, L. Gastroenterology (1982) [Pubmed]
  18. Effect of fasting on the uptake of bilirubin and sulfobromophthalein by the isolated perfused rat liver. Gärtner, U., Goeser, T., Wolkoff, A.W. Gastroenterology (1997) [Pubmed]
  19. Gilbert syndrome and glucose-6-phosphate dehydrogenase deficiency: a dose-dependent genetic interaction crucial to neonatal hyperbilirubinemia. Kaplan, M., Renbaum, P., Levy-Lahad, E., Hammerman, C., Lahad, A., Beutler, E. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  20. Thrombosis and secondary hemochromatosis play major roles in the pathogenesis of jaundiced and spherocytic mice, murine models for hereditary spherocytosis. Kaysser, T.M., Wandersee, N.J., Bronson, R.T., Barker, J.E. Blood (1997) [Pubmed]
  21. Phase I/II trial of cyclosporine as a chemotherapy-resistance modifier in acute leukemia. List, A.F., Spier, C., Greer, J., Wolff, S., Hutter, J., Dorr, R., Salmon, S., Futscher, B., Baier, M., Dalton, W. J. Clin. Oncol. (1993) [Pubmed]
  22. Molecular diagnosis of a familial nonhemolytic hyperbilirubinemia (Gilbert's syndrome) in healthy subjects. Borlak, J., Thum, T., Landt, O., Erb, K., Hermann, R. Hepatology (2000) [Pubmed]
  23. Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6. Cui, Y., König, J., Leier, I., Buchholz, U., Keppler, D. J. Biol. Chem. (2001) [Pubmed]
  24. Immune response to lentiviral bilirubin UDP-glucuronosyltransferase gene transfer in fetal and neonatal rats. Seppen, J., van Til, N.P., van der Rijt, R., Hiralall, J.K., Kunne, C., Elferink, R.P. Gene Ther. (2006) [Pubmed]
  25. Positive predictive value of cholescintigraphy in common bile duct obstruction. Lecklitner, M.L., Austin, A.R., Benedetto, A.R., Growcock, G.W. J. Nucl. Med. (1986) [Pubmed]
  26. Changes in piglet auditory brainstem response amplitudes without increases in serum or cerebrospinal fluid neuron-specific enolase. Hansen, T.W., Cashore, W.J., Oh, W. Pediatr. Res. (1992) [Pubmed]
  27. The effect of bilirubin on biliary iodipamide excretion in the dog. Burgener, F.A., Fischer, H.W. Investigative radiology. (1980) [Pubmed]
  28. Glucose-6-phosphate dehydrogenase deficiency, the UDP-glucuronosyl transferase 1A1 gene, and neonatal hyperbilirubinemia. Huang, C.S., Chang, P.F., Huang, M.J., Chen, E.S., Chen, W.C. Gastroenterology (2002) [Pubmed]
  29. Impact of portal venous pressure on regeneration and graft damage after living-donor liver transplantation. Yagi, S., Iida, T., Taniguchi, K., Hori, T., Hamada, T., Fujii, K., Mizuno, S., Uemoto, S. Liver Transpl. (2005) [Pubmed]
  30. Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice. Saini, S.P., Mu, Y., Gong, H., Toma, D., Uppal, H., Ren, S., Li, S., Poloyac, S.M., Xie, W. Hepatology (2005) [Pubmed]
  31. Interleukin 1beta inhibits CAR-induced expression of hepatic genes involved in drug and bilirubin clearance. Assenat, E., Gerbal-Chaloin, S., Larrey, D., Saric, J., Fabre, J.M., Maurel, P., Vilarem, M.J., Pascussi, J.M. Hepatology (2004) [Pubmed]
  32. Inhibition of human organic anion transporting polypeptide OATP 1B1 as a mechanism of drug-induced hyperbilirubinemia. Campbell, S.D., de Morais, S.M., Xu, J.J. Chem. Biol. Interact. (2004) [Pubmed]
  33. Severe hyperbilirubinemia after creation of transjugular intrahepatic portosystemic shunts: natural history and predictors of outcome. Rouillard, S.S., Bass, N.M., Roberts, J.P., Doherty, C.A., Gee, L., Bacchetti, P., Somberg, K.A. Ann. Intern. Med. (1998) [Pubmed]
  34. Plasminogen activator inhibitor-1 confirms the diagnosis of hepatic veno-occlusive disease in patients with hyperbilirubinemia after bone marrow transplantation. Salat, C., Holler, E., Kolb, H.J., Reinhardt, B., Pihusch, R., Wilmanns, W., Hiller, E. Blood (1997) [Pubmed]
  35. Normal fasting-state levels of serum cholyl-conjugated bile acids in Gilbert's syndrome: an aid to the diagnosis. Vierling, J.M., Berk, P.D., Hofmann, A.F., Martin, J.F., Wolkoff, A.W., Scharschmidt, B.F. Hepatology (1982) [Pubmed]
  36. Interleukin-2 induces profound reversible cholestasis: a detailed analysis in treated cancer patients. Fisher, B., Keenan, A.M., Garra, B.S., Steinberg, S.M., White, D.E., DiBisceglie, A.M., Hoofnagle, J.H., Yolles, P., Rosenberg, S.A., Lotze, M.T. J. Clin. Oncol. (1989) [Pubmed]
  37. Donor liver uridine diphosphate (UDP)-glucuronosyltransferase-1A1 deficiency causing Gilbert's syndrome in liver transplant recipients. Te, H.S., Schiano, T.D., Das, S., Kuan, S.F., DasGupta, K., Conjeevaram, H.S., Baker, A.L. Transplantation (2000) [Pubmed]
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