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Chemical Compound Review:

DMOA N,N-dimethyloctan-1-amine

Synonyms: ACMC-1BB92, AG-B-38033, AG-G-92315, ANW-36392, NSC-63928, ...

Westerlund, D. et al., Kim, B.H. et al., Gluth, W.P. et al., Zhang, J. et al., Hermansson, J. et al.

Kim, Choi, Ok, Zhang, Deng, Fang, McKay,

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High impact information on Dimethyloctylamine

METHODS: An alpha1-acid glycoprotein column was used with the mobile phase containing 0.4% acetic acid and 0.1% dimethyloctylamine, pH 3 [1].
Phosphate buffer, pH 6.20, containing 2-propanol and N,N-dimethyloctylamine was used as mobile phase [2].
The chromatographic support is Nucleosil C18 (5 micron) and the mobile phase is phosphate buffer (pH 2)-acetonitrile (91:9, v/v) with the addition of an aliphatic amine, N,N-dimethyl-N-octylamine (4.10(-4) M), which improves the chromatographic performance [3].
HPLC is performed on a RP-2 10 microns column with a mobile phase of methanol/water (1:1, v/v), to which 0.005 mol/l octanesulfonic acid sodium and 0.003 mol/l dimethyloctylamine are added [4].

Associations of Dimethyloctylamine with other chemical compounds

We have chosen four new quinolones and ciprofloxacin and improved the peak shapes by optimizing the pH of the eluent and the quantity of the additive (N,N-dimethyloctylamine, approximately 0-40 mM) in the monomeric C18 stationary phase [5].

References

Enantioselective analysis of ritalinic acids in biological samples by using a protein-based chiral stationary phase. Zhang, J., Deng, Y., Fang, J., McKay, G. Pharm. Res. (2003) [Pubmed]
Determination of (R)- and (S)-disopyramide in human plasma using a chiral alpha 1-acid glycoprotein column. Hermansson, J., Eriksson, M., Nyquist, O. J. Chromatogr. (1984) [Pubmed]
Reversed-phase chromatography of zimelidine and similar dibasic amines. I. Analysis in biological material. Westerlund, D., Erixson, E. J. Chromatogr. (1979) [Pubmed]
Determination of antileukemic diimidazolinyl compounds in plasma of experimental animals by high-performance liquid chromatography. Gluth, W.P., Dann, O. Die Pharmazie. (1989) [Pubmed]
Comparison of reversed-phase liquid chromatographic methods for the separation of new quinolones. Kim, B.H., Choi, N.H., Ok, J.H. Journal of chromatographic science. (2002) [Pubmed]

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