Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Procyanidin C1 (2S,3R,4S)-2-(3,4- dihydroxyphenyl)-4-[(2S...

Synonyms: Procyanidol C1, CHEMBL290632, SureCN678609, AG-K-64620, CHEBI:75643, ...

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High impact information on Proanthocyanidin C1

Consequently, procyanidin C1 was classified as the most promising antioxidant in-vitro of all compounds tested [1].
Procyanidin C1 was shown to be a good scavenger of both DPPH(*) and HO(*), and a strong inhibitor of lipid peroxidation and the classical pathway of the complement system [1].
Individual cacao polyphenols, flavan-3-ols (catechin and epicatechin), and dimeric (procyanidin B2), trimeric (procyanidin C1), and tetrameric (cinnamtannin A2) proanthocyanidins, and galactopyranosyl-ent-(-)-epicatechin (2alpha-->7, 4alpha-->8)-(-)-epicatechin (Gal-EC-EC), were analyzed by reversed-phase HPLC and/or HPLC/MS [2].

References

Comparative study of eight well-known polyphenolic antioxidants. Cos, P., Hermans, N., Calomme, M., Maes, L., De Bruyne, T., Pieters, L., Vlietinck, A.J., Vanden Berghe, D. J. Pharm. Pharmacol. (2003) [Pubmed]
Analyses of polyphenols in cacao liquor, cocoa, and chocolate by normal-phase and reversed-phase HPLC. Natsume, M., Osakabe, N., Yamagishi, M., Takizawa, T., Nakamura, T., Miyatake, H., Hatano, T., Yoshida, T. Biosci. Biotechnol. Biochem. (2000) [Pubmed]

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