The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Procyanidin B2     (2S,3R,4S)-2-(3,4- dihydroxyphenyl)-4-[(2S...

Synonyms: Procyanidol B2, CHEMBL38714, SureCN288579, CPD-1981, AG-K-50608, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of AIDS-013365


High impact information on AIDS-013365


Biological context of AIDS-013365


Anatomical context of AIDS-013365

  • BACKGROUND: We have previously reported that several selective protein kinase C (PKC) inhibitors, including procyanidin B-2, promote hair epithelial cell growth and stimulate anagen induction [6].

Associations of AIDS-013365 with other chemical compounds


Gene context of AIDS-013365


Analytical, diagnostic and therapeutic context of AIDS-013365


  1. Toxicological studies on procyanidin B-2 for external application as a hair growing agent. Takahashi, T., Yokoo, Y., Inoue, T., Ishii, A. Food Chem. Toxicol. (1999) [Pubmed]
  2. Hyperforin a constituent of St John's wort (Hypericum perforatum L.) extract induces apoptosis by triggering activation of caspases and with hypericin synergistically exerts cytotoxicity towards human malignant cell lines. Hostanska, K., Reichling, J., Bommer, S., Weber, M., Saller, R. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V. (2003) [Pubmed]
  3. The first clinical trial of topical application of procyanidin B-2 to investigate its potential as a hair growing agent. Takahashi, T., Kamimura, A., Yokoo, Y., Honda, S., Watanabe, Y. Phytotherapy research : PTR. (2001) [Pubmed]
  4. Procyanidin B2 has anti- and pro-oxidant effects on metal-mediated DNA damage. Sakano, K., Mizutani, M., Murata, M., Oikawa, S., Hiraku, Y., Kawanishi, S. Free Radic. Biol. Med. (2005) [Pubmed]
  5. Absorption and urinary excretion of procyanidin B2 [epicatechin-(4beta-8)-epicatechin] in rats. Baba, S., Osakabe, N., Natsume, M., Terao, J. Free Radic. Biol. Med. (2002) [Pubmed]
  6. Procyanidin B-2, extracted from apples, promotes hair growth: a laboratory study. Kamimura, A., Takahashi, T. Br. J. Dermatol. (2002) [Pubmed]
  7. The inhibitory effect of tannins on lipid peroxidation of rat heart mitochondria. Hong, C.Y., Wang, C.P., Huang, S.S., Hsu, F.L. J. Pharm. Pharmacol. (1995) [Pubmed]
  8. Procyanidin oligomers counteract TGF-beta1- and TGF-beta2-induced apoptosis in hair epithelial cells: an insight into their mechanisms. Kamimura, A., Takahashi, T., Morohashi, M., Takano, Y. Skin pharmacology and physiology. (2006) [Pubmed]
  9. Procyanidin oligomers selectively and intensively promote proliferation of mouse hair epithelial cells in vitro and activate hair follicle growth in vivo. Takahashi, T., Kamiya, T., Hasegawa, A., Yokoo, Y. J. Invest. Dermatol. (1999) [Pubmed]
  10. Chemoprevention of colorectal cancer by grape seed proanthocyanidin is accompanied by a decrease in proliferation and increase in apoptosis. Nomoto, H., Iigo, M., Hamada, H., Kojima, S., Tsuda, H. Nutrition and cancer. (2004) [Pubmed]
  11. Pharmacological and endocrine effects of Hypericum perforatum and hypericin after repeated treatment. Butterweck, V., Korte, B., Winterhoff, H. Pharmacopsychiatry (2001) [Pubmed]
  12. Antitumor activity of compounds isolated from leaves of Eriobotrya japonica. Ito, H., Kobayashi, E., Li, S.H., Hatano, T., Sugita, D., Kubo, N., Shimura, S., Itoh, Y., Tokuda, H., Nishino, H., Yoshida, T. J. Agric. Food Chem. (2002) [Pubmed]
  13. Catalytic inhibition of human DNA topoisomerase II by interactions of grape cell culture polyphenols. Jo, J.Y., Gonzalez de Mejia, E., Lila, M.A. J. Agric. Food Chem. (2006) [Pubmed]
  14. Several selective protein kinase C inhibitors including procyanidins promote hair growth. Takahashi, T., Kamimura, A., Shirai, A., Yokoo, Y. Skin Pharmacol. Appl. Skin Physiol. (2000) [Pubmed]
  15. Antioxidant activity of polyphenols from seeds of Vitis amurensis in vitro. Wang, J.N., Chen, Y.J., Hano, Y., Nomura, T., Tan, R.X. Acta Pharmacol. Sin. (2000) [Pubmed]
  16. Investigation of topical application of procyanidin B-2 from apple to identify its potential use as a hair growing agent. Kamimura, A., Takahashi, T., Watanabe, Y. Phytomedicine (2000) [Pubmed]
WikiGenes - Universities