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Chemical Compound Review:

Bromine-77 hydrogen bromide

Synonyms: AC1L42VY, 77Br, 15765-39-6, Bromine, isotope of mass 77, Bromine, isotope of mass 77, at.

Spiro, S.G. et al., Brennan, B.L. et al.

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Disease relevance of hydrogen bromide

A technique for the direct labelling of ipratropium bromide with bromine-77, with reconstitution of the drug in a metered dose inhaler so as to be identical to the commercial product, was used to study drug deposition patterns in seven normal subjects and seven patients with chronic bronchitis (mean FEV1 32% (SD 12.2%) predicted normal) [1].

High impact information on hydrogen bromide

Extracellular fluid volume, estimated fro three different techniques (total body chloride, sodium 24, and bromine 77), and total body water were increased significantly above normal values [2].

References

Direct labelling of ipratropium bromide aerosol and its deposition pattern in normal subjects and patients with chronic bronchitis. Spiro, S.G., Singh, C.A., Tolfree, S.E., Partridge, M.R., Short, M.D. Thorax (1984) [Pubmed]
Total body electrolyte composition and distribution of body water in uremia. Brennan, B.L., Yasumura, S., Letteri, J.M., Cohn, S.H. Kidney Int. (1980) [Pubmed]

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