Disease relevance of sodium

• Body weight and urinary sodium/24 hr fell significantly and urinary potassium/24 hr and both supine and standing blood pressure remained unchanged [1].
• Sodium-24 studies in postmastectomy lymphedema [2].
• We therefore investigated the effects of 8 days of treatment with enalapril, 10 mg b.i.d., on sodium balance in 10 subjects with uncomplicated essential hypertension, in balance on a low (50 mmol sodium/24 h) and a liberal (200 mmol sodium/24 h) sodium intake [3].

High impact information on sodium

• RESULTS: Atrial natriuretic peptide given after a 4-hour delay significantly reduced brain water and sodium 24 hours after the injury (P < .05) [4].
• These patients showed significantly higher natriuresis and diuresis following torasemide (26-136 mmol sodium/24 h, median 78 mmol, p < 0.05; 1670-3610 ml urinary volume/24 h, median 2200 ml, p < 0.05) [5].
• Simultaneous elimination of sodium-24, potassium-42, bromium-82, and phosphorus-32 in the determination of trace elements in biological materials by neutron activation analysis [6].
• The extracellular fluid volume was estimated from the simultaneously measured volume of distribution of bromine 77 and sodium 24 [7].
• This has been established by measurements of total body potassium, thiosulfate space, total body sodium, 24 h urine creatinine values and basal metabolic rate [8].

Biological context of sodium

• In 19 nephrotic patients on a dietary intake of 20 mEq sodium/24 hours, indomethacin caused an immediate decrease in glomerular filtration rate (GFR) and urinary protein excretion, an effect completely reversible upon withdrawal of the drug [9].

Associations of sodium with other chemical compounds

• Experimental values of mean attenuation factors are reported for certain tissues in an anthropomorphic phantom irradiated omnidirectionally with gamma rays from sodium-24, radium-226, iodine-131 and xenon-133 [10].

Analytical, diagnostic and therapeutic context of sodium

• Composite ion exchanger for removal of sodium-24 in neutron activation analysis of biological materials [11].
• During the 4 h rehydration recovery period, the runners were allowed to drink a carbohydrate-electrolyte solution (6.9% Lucozade-Sport; sodium, 24 mmol l(-1); potassium, 2.6 mmol l(-1); calcium, 1.2 mmol l(-1); osmolality, 300 mOsm kg(-1)) ad libitum on one occasion [12].

References