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Chemical Compound Review

Nor-udca     (3R)-3-[ (3R,5S,7S,8S,9S,10S,13R,14S,17 R)-3...

Synonyms: CHEMBL1254990, CHEBI:804459, FT-0673148, AC1L4U0K, Norursodeoxycholic Acid, ...
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Disease relevance of Nor-udca


High impact information on Nor-udca


  1. 24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. Fickert, P., Wagner, M., Marschall, H.U., Fuchsbichler, A., Zollner, G., Tsybrovskyy, O., Zatloukal, K., Liu, J., Waalkes, M.P., Cover, C., Denk, H., Hofmann, A.F., Jaeschke, H., Trauner, M. Gastroenterology (2006) [Pubmed]
  2. 5 beta-hydroxylation by the liver. Identification of 3,5,7-trihydroxy nor-bile acids as new major biotransformation products of 3,7-dihydroxy nor-bile acids in rodents. Schteingart, C.D., Hagey, L.R., Setchell, K.D., Hofmann, A.F. J. Biol. Chem. (1993) [Pubmed]
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