Chemical Compound Review:
CHEMBL514958 (2R,3S)-3-(hydroxy-methanoyl- amino)-4...
Synonyms:
GW-3333, CHEBI:556718, AC1Q5NWC, CID216470, DNC000079, ...
- Inhibition of tumor necrosis factor-alpha (TNF-alpha) production and arthritis in the rat by GW3333, a dual inhibitor of TNF-alpha-converting enzyme and matrix metalloproteinases. Conway, J.G., Andrews, R.C., Beaudet, B., Bickett, D.M., Boncek, V., Brodie, T.A., Clark, R.L., Crumrine, R.C., Leenitzer, M.A., McDougald, D.L., Han, B., Hedeen, K., Lin, P., Milla, M., Moss, M., Pink, H., Rabinowitz, M.H., Tippin, T., Scates, P.W., Selph, J., Stimpson, S.A., Warner, J., Becherer, J.D. J. Pharmacol. Exp. Ther. (2001)
- CYP3A induction by N-hydroxyformamide tumor necrosis factor-alpha converting enzyme/matrix metalloproteinase inhibitors use of a pregname X receptor activation assay and primary hepatocyte culture for assessing induction potential in humans. Tippin, T.K., Hamilton, G., Moore, L., Beaudet, E.J., Jolley, S., Brodie, T.A., Andrews, R.C., Becherer, J.D., McDougald, D.L., Gaul, M.D., Hoivik, D.J., Mellon-Kusibab, K., Lehmann, J., Kliewer, S., Novick, S., Laethem, R., Zhao, Z., LeCluyse, E.L. Drug Metab. Dispos. (2003)
- TACE inhibition: a new approach to treating inflammation. Doggrell, S.A. Expert opinion on investigational drugs. (2002)