Gene Review:
Tnf - tumor necrosis factor
Rattus norvegicus
Synonyms:
Cachectin, RATTNF, TNF-a, TNF-alpha, Tnfa, ...
Dheen,
Jun,
Yan,
Tay,
Ling,
Shubayev,
Myers,
Watanobe,
Hayakawa,
Holmes,
Hebert,
Rogers,
Hermann,
Ben-Hur,
Ben-Yosef,
Mizrachi-Kol,
Ben-Menachem,
Miller,
Nakajima,
Tohyama,
Kohsaka,
Kurihara,
Etienne-Manneville,
Chaverot,
Strosberg,
Couraud,
Lewis,
Da,
Li,
Fournier,
Dahle,
Øverland,
Myhre,
Stuestøl,
Hartung,
Krohn,
Mathiesen,
Wang,
Aasen,
- Differential tumor necrosis factor alpha expression by astrocytes from experimental allergic encephalomyelitis-susceptible and -resistant rat strains. Chung, I.Y., Norris, J.G., Benveniste, E.N. J. Exp. Med. (1991)
- TNF-alpha increases expression of IL-6 and ICAM-1 genes through activation of NF-kappaB in osteoblast-like ROS17/2.8 cells. Kurokouchi, K., Kambe, F., Yasukawa, K., Izumi, R., Ishiguro, N., Iwata, H., Seo, H. J. Bone Miner. Res. (1998)
- Hypothalamic interleukin-1 beta and tumor necrosis factor-alpha, but not interleukin-6, mediate the endotoxin-induced suppression of the reproductive axis in rats. Watanobe, H., Hayakawa, Y. Endocrinology (2003)
- Immunocytochemical localization of TNF type 1 and type 2 receptors in the rat spinal cord. Holmes, G.M., Hebert, S.L., Rogers, R.C., Hermann, G.E. Brain Res. (2004)
- Retinoic acid inhibits expression of TNF-alpha and iNOS in activated rat microglia. Dheen, S.T., Jun, Y., Yan, Z., Tay, S.S., Ling, E.A. Glia (2005)
- Dissection of tumor-necrosis factor-alpha inhibition of long-term potentiation (LTP) reveals a p38 mitogen-activated protein kinase-dependent mechanism which maps to early-but not late-phase LTP. Butler, M.P., O'Connor, J.J., Moynagh, P.N. Neuroscience (2004)
- Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor. Colell, A., García-Ruiz, C., Miranda, M., Ardite, E., Marí, M., Morales, A., Corrales, F., Kaplowitz, N., Fernández-Checa, J.C. Gastroenterology (1998)
- Independent suppression of nitric oxide and TNF alpha in the lung of conscious rats by ethanol. Xie, J., Kolls, J., Bagby, G., Greenberg, S.S. FASEB J. (1995)
- Real-time quantitative RT-PCR after laser-assisted cell picking. Fink, L., Seeger, W., Ermert, L., Hänze, J., Stahl, U., Grimminger, F., Kummer, W., Bohle, R.M. Nat. Med. (1998)
- Beneficial autoimmunity to proinflammatory mediators restrains the consequences of self-destructive immunity. Wildbaum, G., Nahir, M.A., Karin, N. Immunity (2003)
- Tumor necrosis factor alpha and interleukin 1beta enhance the cortisone/cortisol shuttle. Escher, G., Galli, I., Vishwanath, B.S., Frey, B.M., Frey, F.J. J. Exp. Med. (1997)
- The phosphatidylinositol 3-kinase/protein kinase B signaling pathway is activated by lipoteichoic acid and plays a role in Kupffer cell production of interleukin-6 (IL-6) and IL-10. Dahle, M.K., Øverland, G., Myhre, A.E., Stuestøl, J.F., Hartung, T., Krohn, C.D., Mathiesen, Ø., Wang, J.E., Aasen, A.O. Infect. Immun. (2004)
- The anti-inflammatory effect of curcumin in an experimental model of sepsis is mediated by up-regulation of peroxisome proliferator-activated receptor-gamma. Siddiqui, A.M., Cui, X., Wu, R., Dong, W., Zhou, M., Hu, M., Simms, H.H., Wang, P. Crit. Care Med. (2006)
- The effects of cobalt chromium upon macrophages. Horowitz, S.M., Luchetti, W.T., Gonzales, J.B., Ritchie, C.K. J. Biomed. Mater. Res. (1998)
- Dilinoleoylphosphatidylcholine decreases acetaldehyde-induced TNF-alpha generation in Kupffer cells of ethanol-fed rats. Cao, Q., Mak, K.M., Lieber, C.S. Biochem. Biophys. Res. Commun. (2002)
- 5-Aza-2'-deoxycytidine stimulates inducible nitric oxide synthase induction in C6 astrocytoma cells. Cvetkovic, I., Popadic, D., Vuckovic, O., Harhaji, L.j., Miljkovic, D.j., Trajkovic, V. Brain Res. (2004)
- The role of protein kinase B and mitogen-activated protein kinase in epidermal growth factor and tumor necrosis factor alpha-mediated rat hepatocyte survival and apoptosis. Roberts, R.A., James, N.H., Cosulich, S.C. Hepatology (2000)
- Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases. Bradham, C.A., Stachlewitz, R.F., Gao, W., Qian, T., Jayadev, S., Jenkins, G., Hannun, Y., Lemasters, J.J., Thurman, R.G., Brenner, D.A. Hepatology (1997)
- Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner. de Alvaro, C., Teruel, T., Hernandez, R., Lorenzo, M. J. Biol. Chem. (2004)
- Experimental intestinal endometriosis is characterized by increased levels of soluble TNFRSF1B and downregulation of Tnfrsf1a and Tnfrsf1b gene expression. Rojas-Cartagena, C., Appleyard, C.B., Santiago, O.I., Flores, I. Biol. Reprod. (2005)
- Inducible nitric oxide synthase in rat hepatic lipocytes and the effect of nitric oxide on lipocyte contractility. Rockey, D.C., Chung, J.J. J. Clin. Invest. (1995)
- Insulin-like growth factor I inhibits induction of nitric oxide synthase in vascular smooth muscle cells. Schini, V.B., Catovsky, S., Schray-Utz, B., Busse, R., Vanhoutte, P.M. Circ. Res. (1994)
- Mechanisms of endotoxin-induced NO, IL-6, and TNF-alpha production in activated rat hepatic stellate cells: role of p38 MAPK. Thirunavukkarasu, C., Watkins, S.C., Gandhi, C.R. Hepatology (2006)
- Cytosolic phospholipase A2 is required for cytokine-induced expression of type IIA secretory phospholipase A2 that mediates optimal cyclooxygenase-2-dependent delayed prostaglandin E2 generation in rat 3Y1 fibroblasts. Kuwata, H., Nakatani, Y., Murakami, M., Kudo, I. J. Biol. Chem. (1998)
- ICAM-1-coupled signaling pathways in astrocytes converge to cyclic AMP response element-binding protein phosphorylation and TNF-alpha secretion. Etienne-Manneville, S., Chaverot, N., Strosberg, A.D., Couraud, P.O. J. Immunol. (1999)
- Tumor necrosis factor-alpha and interferon-gamma suppress both gene expression and deoxyribonucleic acid-binding of TTF-2 in FRTL-5 cells. Miyazaki, A., Shimura, H., Endo, T., Haraguchi, K., Onaya, T. Endocrinology (1999)
- Nuclear factor-kappa B mediates induction of vascular cell adhesion molecule-1 in glomerular mesangial cells. Khachigian, L.M., Collins, T., Fries, J.W. Biochem. Biophys. Res. Commun. (1995)
- Peptide YY attenuates transcription factor activity in tumor necrosis factor-alpha-induced pancreatitis. Vona-Davis, L., Yu, A., Magabo, K., Evans, T., Jackson, B., Riggs, D., McFadden, D. J. Am. Coll. Surg. (2004)
- Tumor necrosis factor alpha decreases 1,25-dihydroxyvitamin D3 receptors in osteoblastic ROS 17/2.8 cells. Mayur, N., Lewis, S., Catherwood, B.D., Nanes, M.S. J. Bone Miner. Res. (1993)
- Involvement of p42/44 MAPK and RhoA protein in augmentation of ACh-induced bronchial smooth muscle contraction by TNF-alpha in rats. Sakai, H., Otogoto, S., Chiba, Y., Abe, K., Misawa, M. J. Appl. Physiol. (2004)
- Tumor necrosis factor-alpha and malnutrition-induced inhibition of diaphragm fiber growth in young rats. Lewis, M.I., Da, X., Li, H., Fournier, M. J. Appl. Physiol. (2005)
- Axonal transport of TNF-alpha in painful neuropathy: distribution of ligand tracer and TNF receptors. Shubayev, V.I., Myers, R.R. J. Neuroimmunol. (2001)
- Differential modulation of astrocyte cytokine gene expression by TGF-beta. Benveniste, E.N., Kwon, J., Chung, W.J., Sampson, J., Pandya, K., Tang, L.P. J. Immunol. (1994)
- Convergence of redox-sensitive and mitogen-activated protein kinase signaling pathways in tumor necrosis factor-alpha-mediated monocyte chemoattractant protein-1 induction in vascular smooth muscle cells. De Keulenaer, G.W., Ushio-Fukai, M., Yin, Q., Chung, A.B., Lyons, P.R., Ishizaka, N., Rengarajan, K., Taylor, W.R., Alexander, R.W., Griendling, K.K. Arterioscler. Thromb. Vasc. Biol. (2000)
- Protein kinase C alpha requirement in the activation of p38 mitogen-activated protein kinase, which is linked to the induction of tumor necrosis factor alpha in lipopolysaccharide-stimulated microglia. Nakajima, K., Tohyama, Y., Kohsaka, S., Kurihara, T. Neurochem. Int. (2004)
- Cytokine-mediated modulation of MMPs and TIMPs in multipotential neural precursor cells. Ben-Hur, T., Ben-Yosef, Y., Mizrachi-Kol, R., Ben-Menachem, O., Miller, A. J. Neuroimmunol. (2006)
- Cytokine mRNA expression in postischemic/reperfused myocardium. Herskowitz, A., Choi, S., Ansari, A.A., Wesselingh, S. Am. J. Pathol. (1995)
- Regulatory effects of eotaxin on acute lung inflammatory injury. Guo, R.F., Lentsch, A.B., Warner, R.L., Huber-Lang, M., Sarma, J.V., Hlaing, T., Shi, M.M., Lukacs, N.W., Ward, P.A. J. Immunol. (2001)
- Activation of mitogen-activated protein kinase p38 and extracellular signal-regulated kinase is involved in glass fiber-induced tumor necrosis factor-alpha production in macrophages. Ye, J., Zeidler, P., Young, S.H., Martinez, A., Robinson, V.A., Jones, W., Baron, P., Shi, X., Castranova, V. J. Biol. Chem. (2001)
- Tumor necrosis factor-alpha modulates the expression of its p60 receptor and several cytokines in rat tracheal epithelial cells. Bader, T., Nettesheim, P. J. Immunol. (1996)
- ICAM-1-induced expression of proinflammatory cytokines in astrocytes: involvement of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways. Lee, S.J., Drabik, K., Van Wagoner, N.J., Lee, S., Choi, C., Dong, Y., Benveniste, E.N. J. Immunol. (2000)