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Chemical Compound Review

CHEMBL164131     N,N-diprop-2-enylnitrous amide

Synonyms: CCRIS 6153, NSC-37648, LS-7130, NSC37648, NSC 37648, ...
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Disease relevance of N-Nitrosodiallylamine

  • Weekly intragastric administration of 20, 40, and 80 mg/kg body weight diallylnitrosamine to BD IX rats selectively induced nasal and paranasal cavity tumors with incidences of 30%, 85%, and 65% in females and of 0%, 75%, and 80% in males, respectively [1].

High impact information on N-Nitrosodiallylamine


Associations of N-Nitrosodiallylamine with other chemical compounds


  1. Selective induction of nasal cavity tumors in rats by diallylnitrosamine. Pour, P.M., Grandjean, C.J., Knepper, S. J. Cancer Res. Clin. Oncol. (1985) [Pubmed]
  2. Carcinogenicity of diallylnitrosamine following intragastric administration to Syrian hamsters. Grandjean, C.J., Althoff, J., Pour, P.M. J. Natl. Cancer Inst. (1985) [Pubmed]
  3. Metabolism of N-nitrosodi-n-propylamine and N-nitrosodiallylamine by isolated rat hepatocytes. Bauman, P.A., Hotchkiss, J.H., Parker, R.S. Cancer Lett. (1985) [Pubmed]
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