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Chemical Compound Review:

Carnidazol 1-methoxy-N-[2-(2-methyl-5- nitro-imidazol...

Synonyms: Carnidazole, Carnidazolum, CHEMBL135000, NSC-293873, AC1MHV2H, ...

de Armas, H.N. et al., Munoz, E. et al., Chaudhuri, P. et al., Franssen, F.F. et al.

de Armas, Peeters, Blaton, Van den Mooter, De Ridder, Schenk,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of ME 108

The values of the torsion angles for the molecules of the two polymorphic forms and the hydrate of carnidazole are compared to those obtained from the conformational search [1].

High impact information on ME 108

The in vitro susceptibility of four T. gallinae isolates to five nitroimidazolic drugs, that is, carnidazole, dimetridazole, metronidazole, ornidazole and ronidazole, was also determined [2].
Six out of eight different Trichomonas gallinae strains isolated from racing pigeons proved to be resistant to the nitroimidazole drugs ronidazole, carnidazole and metronidazole [3].
A double-blind controlled clinical trial of the new, not yet commercially available drug, carnidazole and tinidazole, was carried out in 77 women with a proven vaginal trichomoniasis [4].

Analytical, diagnostic and therapeutic context of ME 108

Crystal structure of carnidazole form II from synchrotron X-ray powder diffraction: Structural comparison with form I, the hydrated form and the low energy conformations in vacuo [1].

References

Crystal structure of carnidazole form II from synchrotron X-ray powder diffraction: Structural comparison with form I, the hydrated form and the low energy conformations in vacuo. de Armas, H.N., Peeters, O.M., Blaton, N., Van den Mooter, G., De Ridder, D.J., Schenk, H. Journal of pharmaceutical sciences. (2006) [Pubmed]
In vivo and in vitro sensitivity of Trichomonas gallinae to some nitroimidazole drugs. Munoz, E., Castella, J., Gutierrez, J.F. Vet. Parasitol. (1998) [Pubmed]
In vitro nitroimidazole resistance of Trichomonas gallinae and successful therapy with an increased dosage of ronidazole in racing pigeons (Columba livia domestica). Franssen, F.F., Lumeij, J.T. J. Vet. Pharmacol. Ther. (1992) [Pubmed]
A double-blind controlled clinical trial of carnidazole and tinidazole in the treatment of vaginal trichomoniasis. Chaudhuri, P., Drogendijk, A.C. Eur. J. Obstet. Gynecol. Reprod. Biol. (1980) [Pubmed]

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