Disease relevance of NITROANILINE

• In in vitro studies, the capacity of 1,3-DNB and 1,3-DNB metabolites (nitroaniline, nitroacetanilide, aminoacetanilide, diacetamidobenzene) to induce methemoglobinemia was examined in suspensions of red blood cells obtained from both species [1].

High impact information on NITROANILINE

• We demonstrate full intercalation of the nitroaniline group of these reporter molecules between base pairs, based on large upfield proton shifts (1.3-1.7 ppm) at all four aromatic proton markers on complex formation [2].
• Either human lung mast cell supernatants or authentic mast cell tryptase were mixed with benzoyl-DL-arginine-p-nitroaniline and incubated for up to 72 h at 37 degrees C. The appearance of nitroaniline was then measured at 410 nm in an ELISA plate reader [3].
• Sorption of ionizable organic compounds (IOCs), 2,4-dichlorophenol (DCP), p-nitroaniline (NA) and benzoic acid (BA), on the modified soil was determined under different pH conditions [4].
• Finally, protein C can be activated by APC as indicated by the increase in APC specific synthetic substrate Tryp-Arg-Arg-p nitroaniline hydrolysis [5].
• Hydrogen bonding in nitroaniline analogues: 4-nitrobenzaldehyde hydrazone forms hydrogen-bonded sheets of R4 4(26) rings [6].

Analytical, diagnostic and therapeutic context of NITROANILINE

• The MALDI spectra obtained with the neutral compounds ANA (pH 4.4), NA (pH 6.4) and AMNP (pH 7.1) as matrices contain only peaks of the subunit with no signal of the non-covalent bound complexes present [7].
• This paper deals with the separation of isomers of nitroaniline by liquid chromatography using the ligand-exchange technique [8].

References