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Chemical Compound Review:

Narirutin (2S)-5-hydroxy-2-(4- hydroxyphenyl)-7-[(2S...

Synonyms: Isonaringin, Isonaringenin, CHEMBL446246, SureCN669946, CHEBI:28705, ...

Gel-Moreto, N. et al., Kim, H.K. et al., Wistuba, D. et al., Leuzzi, U. et al., Manach, C. et al.

Wistuba, Trapp, Gel-Moreto, Galensa, Schurig, Leuzzi, Caristi, Panzera, Licandro,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Narirutin

Temperature- and pH-dependent enantiomerization or epimerization barriers of several flavanones (naringenin, homoeriodictyol) and flavanone-7-O-glycosides (naringin, neohesperidin, prunin, narirutin) in basic media (pH values of 9-11) have been observed [1].
By bioactivity-guided fractionation, a new flavanone triglycoside, naringenin 7-O-(2",6"-di-O-alpha-rhamnopyranosyl)-beta-glucopyranoside (1), as well as hesperetin 7-O-(2", 6"-di-O-alpha-rhamnopyranosyl)-beta-glucopyranoside (2), hesperidin (3) and narirutin (4) have been isolated from the fruits of Citrus junos Tanaka (Rutaceae) [2].
The diastereomers of six major flavanone-7-O-glycosides (naringin, prunin, narirutin, hesperidin, neohesperidin and eriocitrin) were completely separated for the first time by chiral capillary electrophoresis (CE) employing various buffers and chiral selectors on the basis of the results achieved in 1998 in our research group by Mellenthin [3].
Bioavailability in humans of the flavanones hesperidin and narirutin after the ingestion of two doses of orange juice [4].

Analytical, diagnostic and therapeutic context of Narirutin

An increased narirutin/hesperidin ratio after centrifugation and the presence of high amounts of PMFs in SPEs, which remain unchanged after centrifugation, were observed [5].

References

Stereoisomeric separation of flavanones and flavanone-7-O-glycosides by capillary electrophoresis and determination of interconversion barriers. Wistuba, D., Trapp, O., Gel-Moreto, N., Galensa, R., Schurig, V. Anal. Chem. (2006) [Pubmed]
Flavanone glycosides from Citrus junos and their anti-influenza virus activity. Kim, H.K., Jeon, W.K., Ko, B.S. Planta Med. (2001) [Pubmed]
Chiral separation of six diastereomeric flavanone-7-O-glycosides by capillary electrophoresis and analysis of lemon juice. Gel-Moreto, N., Streich, R., Galensa, R. Journal of chromatography. A. (2001) [Pubmed]
Bioavailability in humans of the flavanones hesperidin and narirutin after the ingestion of two doses of orange juice. Manach, C., Morand, C., Gil-Izquierdo, A., Bouteloup-Demange, C., Rémésy, C. European journal of clinical nutrition. (2003) [Pubmed]
Flavonoids in pigmented orange juice and second-pressure extracts. Leuzzi, U., Caristi, C., Panzera, V., Licandro, G. J. Agric. Food Chem. (2000) [Pubmed]

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